- BREAST CANCER-RESISTANT PROTEIN INHIBITOR
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The invention provides a cancer cell useful in screening BCRP-inhibitors, and a BCRP-inhibitor.The BCRP-inhibitor contains, as the active ingredient, a flavonoid represented by any of the following formulae (1), (2), (3), (4), and (5): and glycosides, est
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Page/Page column 13-14
(2008/06/13)
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- PROTOGENKWANIN, A NEW FLAVONOID FROM EQUISETUM ARVENSE L.
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From the fertile sprouts of Equisetum arvense L. have been isolated protogenkwanin-4'-glucoside and gossypitrin.The structure of protogenkwanin as 5-hydroxy-2-(1,4-dihydroxy-2,5-cyclohexadienyl)-7-methoxy-4-chromenon is proved on the basis of chemical and physical evidence.It is demonstrated that articulatin, a thiamine decomposing substance, from E. arvense, is identical with the known flavonol glycoside gossypitrine (=gossypetin-7-glucoside).The synthesis of 2,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4-chromanon is reported.
- Hauteville, Marcelle,Chopin, Jean,Geiger, Hans,Schuler, Lothar
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p. 377 - 381
(2007/10/02)
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