204919-70-0Relevant articles and documents
Practical, modular, and general synthesis of 3-coumaranones through gold-catalyzed intermolecular alkyne oxidation strategy
Shu, Chao,Liu, Rongfu,Liu, Shuang,Li, Jian-Qiao,Yu, Yong-Fei,He, Qiao,Lu, Xin,Ye, Long-Wu
supporting information, p. 91 - 95 (2015/02/19)
A gold-catalyzed intermolecular alkyne oxidation for the preparation of 3-coumaranones has been developed. Using 8-isopropylquinoline N-oxides as oxidants, the reactions of o-ethynylanisoles afford versatile 3-coumaranones in moderate to good isolated yields. The synthetic utility of this chemistry is also indicated by the synthesis of the natural product sulfuretin.
Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles
Patrick, Donald A.,Bakunov, Stanislav A.,Bakunova, Svetlana M.,Kumar, E.V.K. Suresh,Lombardy, Richard J.,Jones, Susan Kilgore,Bridges, Arlene S.,Zhirnov, Oksana,Hall, James Edwin,Wenzler, Tanja,Brun, Reto,Tidwell, Richard R.
, p. 2468 - 2485 (2008/02/03)
3,5-Bis(4-amidinophenyl)isoxazole (3) - an analogue of 2,5-bis(4- amidinophenyl)furan (furamidine) in which the central furan ring is replaced by isoxazole - and 42 novel analogues were prepared by two general synthetic pathways. The 43 isoxazole derivati
Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
-
Page/Page column 24-26; 38, (2010/11/24)
Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.
