205443-23-8 Usage
Uses
Used in Pharmaceutical Research and Development:
(R)-1-Benzyl-azetidine-2-carboxylic acid methyl ester is utilized as a key intermediate in the synthesis of various drugs and bioactive molecules. Its unique molecular structure allows for the exploration of structure-activity relationships of bioactive compounds, thereby enhancing the discovery and development of new pharmaceutical agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-1-Benzyl-azetidine-2-carboxylic acid methyl ester is employed as a valuable tool for studying the interactions between chemical compounds and biological targets. Its structural features contribute to a better understanding of the mechanisms of action of potential drugs, facilitating the optimization of drug candidates for improved efficacy and safety.
Used in Drug Synthesis:
(R)-1-Benzyl-azetidine-2-carboxylic acid methyl ester is used as a starting material or intermediate in the synthesis of complex drug molecules. Its reactivity and functional groups enable the formation of diverse chemical entities, which can be further modified to achieve desired pharmacological properties.
Used in Drug Discovery:
In drug discovery, (R)-1-Benzyl-azetidine-2-carboxylic acid methyl ester serves as a versatile scaffold for the design of novel bioactive compounds. Its unique structural features can be exploited to develop new chemical entities with potential therapeutic applications, contributing to the advancement of pharmaceutical research.
Overall, (R)-1-Benzyl-azetidine-2-carboxylic acid methyl ester holds significant potential in the pharmaceutical industry, playing a vital role in the synthesis, research, and development of innovative drug candidates and bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 205443-23-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,4,4 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 205443-23:
(8*2)+(7*0)+(6*5)+(5*4)+(4*4)+(3*3)+(2*2)+(1*3)=98
98 % 10 = 8
So 205443-23-8 is a valid CAS Registry Number.
205443-23-8Relevant articles and documents
Highly efficient and enantioselective biotransformations of racemic azetidine-2-carbonitriles and their synthetic applications
Leng, Dong-Hui,Wang, De-Xiang,Pan, Jie,Huang, Zhi-Tang,Wang, Mei-Xiang
experimental part, p. 6077 - 6082 (2009/12/26)
(Chemical Equation Presented) Catalyzed by the Rhodococcus erythropolis AJ270 whole cell catalyst in neutral aqueous buffer at 30 °C, a number of racemic 1-benzylazetidine-2-carbonitriles, trans-1-benzyl-4-methylazetidine-2- carbonitrile, and 1-benzyl-2-m
Enzymatic resolution of methyl N-alkyl-azetidine-2-carboxylates by Candida antarctica lipase-mediated ammoniolysis
Starmans, Wim A. J.,Doppen, Roy G.,Thijs, Lambertus,Zwanenburg, Binne
, p. 429 - 435 (2007/10/03)
A facile method for the synthesis of optically active azetidine-2- carboxylic acid derivatives is presented Racemic N-alkylated azetidine esters are resolved by lipase from Candida antarctica in an ammoniolysis reaction, and both the S-amide and the R-ester are obtained with excellent stereoselectivity.
