- Synthesis and nematicidal activities of 1,2,3-benzotriazin-4-one derivatives containing thiourea and acylthiourea against Meloidogyne incognita
-
Two series of novel 1,2,3-benzotriazin-4-one derivatives containing thiourea and acylthiourea were designed and synthesized. The bioassay results showed that most of the test compounds showed good nematicidal activity against M. incognita at the concentration of 10.0?mg?L?1 in vivo. The compounds A13, A17 and B3 showed excellent nematicidal activity on the second stage juveniles of the root-knot nematode with the inhibition rate of 51.3%, 58.3% and 51.3% at the concentration of 1.0?mg?L?1 respectively. It suggested that the structure of 1,2,3-benzotriazin-4-one derivatives containing thiourea and acylthiourea could be optimized further.
- Chang, Yaning,Zhang, Jingwei,Chen, Xiulei,Li, Zhong,Xu, Xiaoyong
-
p. 2641 - 2644
(2017/05/10)
-
- Isothiocyanation of amines using the Langlois reagent
-
The Langlois reagent was found to be effective for the isothiocyanation of primary amines in the presence of copper iodide and diethyl phosphonate.
- Liao, Yan-Yan,Deng, Jian-Chao,Ke, Yan-Ping,Zhong, Xiao-Lin,Xu, Li,Tang, Ri-Yuan,Zheng, Wenxu
-
supporting information
p. 6073 - 6076
(2017/07/10)
-
- Synthesis of isothiocyanates by reaction of amines with phenyl chlorothionoformate via one-pot or two-step process
-
A facile and efficient synthesis of isothiocyanates from amines is described. This method involves the reaction of amines with phenyl chlorothionoformate in the presence of solid sodium hydroxide by either a one-pot process or a two-step approach. The one-pot process is useful for preparing alkyl and electron-rich aryl isothiocyanates, whereas the two-step approach is more versatile, working very well not only for alkyl and electron-rich aryl isothiocyanates, but also for highly electron-deficient aryl and heterocyclic isothiocyanates. Georg Thieme Verlag Stuttgart, New York.
- Li, Zheng-Yi,Ma, Hong-Zhao,Han, Chen,Xi, Hai-Tao,Meng, Qi,Chen, Xin,Sun, Xiao-Qiang
-
p. 1667 - 1674
(2013/07/19)
-
- Cytostatic tetrazole-butenolide conjugates: Linking tetrazole and butenolide rings via stille coupling and biological activity of the target substances
-
A series of tetrazoles linked to the butenolide core via benzene rings were prepared by the Stille coupling reaction of α-(tributylstannyl) butenolides and 5-(alkylsulfanyl)-1-(4-iodophenyl)tetrazoles, and the compounds were tested for antifungal and cytostatic activity. Interesting antifungal activities against the filamentous strain Absidia corymbifera, and cytostatic activities against leukemic cells HL-60 and CCRF-CEM were found. The cytostatic activity requires the presence of both the butenolide ring and the alkylsulfanyl group bound to tetrazole ring. In addition, the feasibility of Pd-coupling reactions with 5-iodotetrazoles was evaluated.
- Balsanek, Vojtech,Tichotova, Lucie,Kunes, Jiri,Spulak, Marcel,Pour, Milan,Votruba, Ivan,Buchta, Vladimir
-
scheme or table
p. 1161 - 1178
(2010/04/28)
-
- Synthesis and Reaction of 2-Imino-1,3-thiazetidines and 2-Imino-1,3-dithietanes
-
2-Imino-1,3-thiazetidines and 2-imino-1,3-dithietanes were synthesized and their reactivities were studied.The former readily underwent ring-opening reaction with amines to yield guanidine derivatives.The reaction products were applied to the synthesis of heterocycles such as triazoles and triazines.The latter was converted to isothiocyanate by the reaction of m-chloroperbenzoic acid.
- Okajima, Nobuyuki,Okada, Yoshiyuki
-
p. 177 - 185
(2007/10/02)
-
- Alkanimidoylthioureas
-
The compounds of this invention are novel alkanimidoylthioureas having antifertility activity. They are prepared by the reaction of appropriate alkanamidines with appropriate isothiocyanates.
- -
-
-