206182-51-6

Basic information

• Product Name: 1-Piperidinecarbonyl chloride, 4-oxo- (9CI)
• Synonyms: 1-Piperidinecarbonyl chloride, 4-oxo- (9CI)
• CAS NO: 206182-51-6
• Molecular Formula: C6H8ClNO2
• Molecular Weight: 161.58622
• Product Categories: ACIDHALIDE
• Mol File: 206182-51-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Piperidinecarbonyl chloride, 4-oxo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarbonyl chloride, 4-oxo- (9CI)(206182-51-6)
• EPA Substance Registry System: 1-Piperidinecarbonyl chloride, 4-oxo- (9CI)(206182-51-6)

Safety Data

• Hazardous Substances Data: 206182-51-6(Hazardous Substances Data)

Usage

Physical appearance

White to light yellow solid at room temperature

Solubility

Soluble in water and ethanol

Chemical classification

Derivative of piperidine (a six-membered heterocyclic amine)

Uses

Reagent in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals; versatile building block for the synthesis of various heterocyclic compounds; precursor in the production of other chemical compounds

Hazards

Corrosive and toxic; should be handled with care and stored in a tightly sealed container in a well-ventilated area.

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 32315-10-9 bis(trichloromethyl) carbonate 

Relevant articles and documents

Use of triphosgene for direct preparation of carbamoyl chlorides from tertiary benzylamines

A general method for direct preparation of carbamoyl chlorides from corresponding benzylamines using triphosgene is described.

Thiazolo-pyrimidine/pyridine urea derivatives

There are presented compounds of the formula or a pharmaceutically acceptable salt thereof, which are active adenosine A2B receptor antagonists and useful in the treatment of diabetes, diabetic retinopathy, asthma and diarrhea.

Selective cleavage of N-benzyl-protected secondary amines by triphosgene

A series of competition experiments has revealed that selective cleavage of N-benzyl-protected secondary amines can be achieved with triphosgene, thereby providing a useful range of carbamoyl chlorides.