206357-78-0

Basic information

• Product Name: 3-Chloro-2-(tributylstannyl)pyridine
• Synonyms: 3-Chloro-2-(tributylstannyl)pyridine;2-(Tributylstannyl)-3-chloropyridine;tributyl-(3-chloropyridin-2-yl)stannane
• CAS NO: 206357-78-0
• Molecular Formula: C17H30ClNSn
• Molecular Weight: 402.594
• Product Categories: Stannanes
• Mol File: 206357-78-0.mol

Chemical Properties

• Boiling Point: 397.2°C at 760 mmHg
• Flash Point: 194°C
• Appearance: /
• Vapor Pressure: 3.69E-06mmHg at 25°C
• PKA: 2.92±0.29(Predicted)
• CAS DataBase Reference: 3-Chloro-2-(tributylstannyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-2-(tributylstannyl)pyridine(206357-78-0)
• EPA Substance Registry System: 3-Chloro-2-(tributylstannyl)pyridine(206357-78-0)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 36/37-45
• RIDADR: UN 2788 6.1 / PGII
• WGK Germany: 3
• Hazardous Substances Data: 206357-78-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Chloro-2-(tributylstannyl)pyridine is utilized as a reagent for the introduction of the tributylstannyl group into various organic molecules. Its application is crucial in the synthesis of complex organic compounds, where the tributylstannyl group serves as a versatile precursor for additional chemical reactions.
Used in Chemical Reactions as a Precursor:
The tributylstannyl group in 3-Chloro-2-(tributylstannyl)pyridine is used as a precursor in chemical reactions, enabling the formation of new organic molecules with desired properties. This makes the compound an essential component in the development of advanced organic materials and pharmaceuticals.
Used in Further Functionalization of Molecules:
The chloro group present in 3-Chloro-2-(tributylstannyl)pyridine is used for further functionalization of the molecule. This allows for the attachment of other functional groups or the alteration of the molecule's properties, expanding its applications in various chemical and industrial processes.
Used in Research and Development:
3-Chloro-2-(tributylstannyl)pyridine is employed in research and development settings to explore new synthetic pathways and investigate the compound's potential in creating novel organic molecules with unique characteristics and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Chloro-2-(tributylstannyl)pyridine is used as a building block for the synthesis of new drug candidates. Its ability to introduce the tributylstannyl group and the chloro group into organic molecules makes it a valuable tool in the development of innovative pharmaceutical compounds with potential therapeutic applications.
Used in Material Science:
3-Chloro-2-(tributylstannyl)pyridine is utilized in material science for the synthesis of advanced materials with specific properties. 3-Chloro-2-(tributylstannyl)pyridine's ability to participate in various chemical reactions allows for the creation of materials with tailored characteristics for use in different industries, such as electronics, coatings, and polymers.

InChI:InChI=1/C5H3ClN.3C4H9.Sn/c6-5-2-1-3-7-4-5;3*1-3-4-2;/h1-3H;3*1,3-4H2,2H3;/rC17H30ClNSn/c1-4-7-13-20(14-8-5-2,15-9-6-3)17-16(18)11-10-12-19-17/h10-12H,4-9,13-15H2,1-3H3

Upstream product

• 96424-68-9 2-bromo-3-chloropyridine 
• 1461-22-9 tributyltin chloride 

Relevant articles and documents

4,4A,5,7,8,8A-HEXAPYRIDO[4,3-B][1,4]OXAZIN-3-ONE COMPOUNDS AS MAGL INHIBITORS

The invention provides new heterocyclic compounds having the general formula (I) wherein A, B, L1, X, m, n, and R1 to R7 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as monoacylglycerol lipase (MAGL) inhibitors.

MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS

The invention relates to modulators of Embryonic Ectoderm Development (EED) and/or Polycomb Repressive Complex 2 (PRC2) useful in the treatment of disorders and diseases associated with EEC and PRC2, being macrocyclic azolopyridine derivatives and compositions thereof of Formula (I), or a pharmaceutically acceptable salt, prodrug, solvate, hydrate, enantiomer, isomer, or tautomer thereof, wherein X1, X2, X3, A1, A2, Y, R1, R2, R3, and R4 are as described herein.

PYRAZOLO[1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted pyrazolo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrazolo[1,5-a]pyrimidinyl carboxamide compounds described herein include 2-heterocyclyl-4-alkyl-pyrazolo[1,5-a]pyrirnidine-3-carboxarnide compounds and variants thereof.