206430-59-3Relevant articles and documents
Synthesis and structure-activity relationships of a new model of arylpiperazines 4. 1-[ω-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene)- 2,5-pyrrolidinediones and -3-(9h-fluoren-9-ylidene)-2,5-pyrrolidinediones: Study of the steric requirements of the
López-Rodríguez, María L.,Morcillo, M. José,Rovat, Tandú K.,Fernández, Esther,Vicente, Bruno,Sanz, Antonio M.,Hernández, Medardo,Orensanz, Luis
, p. 36 - 49 (2007/10/03)
In the present paper, we report the synthesis and the binding profile on 5-HT(1A), α1 and D2 receptors of a new series of 1-[ω-(4-arylpiperazin- 1-yl)alkyl]-3-(diphenylmethylene)-2,5-pyrrolidinediones (III) (1-4) and -3- (9H-fluoren-
1-[ω-(4-arylpiperazin-1-yl)alkyl]-3-diphenylmethylene-2,5-pyrrolidinediones as 5-HT(1A) receptor ligands: Study of the steric requirements of the terminal amide fragment on 5-HT(1A) affinity/selectivity
Lopez-Rodriguez, Maria L.,Morcillo, M. Jose,Rovat, Tandu K.,Fernandez, Esther,Sanz, Antonio M.,Orensanz, Luis
, p. 581 - 586 (2007/10/03)
In the present paper, we report the synthesis and the binding profile on 5-HT(1A), α1 and D2 receptors of a new series of imide-arylpiperazines 3. The study of the length of the alkyl chain and the imide substructure allows us to sug