206559-62-8

Basic information

• Product Name: 3-ETHOXY-2-HYDROXY-BETA-NITROSTYRENE
• Synonyms: 1-(3-ETHOXY-2-HYDROXYPHENYL)-2-NITROETHENE;3-ETHOXY-2-HYDROXY-BETA-NITROSTYRENE;3-ETHOXY-2-HYDROXY-B-NITROSTYRENE;Phenol, 2-ethoxy-6-(2-nitroethenyl)- (9CI)
• CAS NO: 206559-62-8
• Molecular Formula: C₁₀H₁₁NO₄
• Molecular Weight: 209.2
• Product Categories: ETHOXY
• Mol File: 206559-62-8.mol

Chemical Properties

• Melting Point: 115-117°C
• Boiling Point: 359.1°C at 760 mmHg
• Flash Point: 171°C
• Appearance: /
• Density: 1.263g/cm³
• Vapor Pressure: 1.18E-05mmHg at 25°C
• Refractive Index: 1.6
• CAS DataBase Reference: 3-ETHOXY-2-HYDROXY-BETA-NITROSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ETHOXY-2-HYDROXY-BETA-NITROSTYRENE(206559-62-8)
• EPA Substance Registry System: 3-ETHOXY-2-HYDROXY-BETA-NITROSTYRENE(206559-62-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 206559-62-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Ethoxy-2-hydroxy-beta-nitrostyrene is used as a key intermediate in the synthesis of various organic compounds due to its reactive functional groups. Its nitro and hydroxyl groups facilitate multiple chemical reactions, making it a valuable component in the creation of a wide range of organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-Ethoxy-2-hydroxy-beta-nitrostyrene is used as a precursor in the synthesis of pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Antimicrobial Applications:
3-Ethoxy-2-hydroxy-beta-nitrostyrene has been studied for its antimicrobial properties, making it a potential candidate for use in the development of new antimicrobial agents. Its ability to inhibit the growth of certain microorganisms could contribute to the creation of more effective treatments for bacterial infections.
Used in Antifungal Applications:
Similarly, this compound has also been investigated for its antifungal properties. Its potential use in antifungal applications could lead to the development of new treatments for fungal infections, addressing the need for novel antifungal agents in the medical field.

InChI:InChI=1/C10H11NO4/c1-2-15-9-5-3-4-8(10(9)12)6-7-11(13)14/h3-7,12H,2H2,1H3/b7-6+

Upstream product

• 75-52-5 nitromethane 
• 492-88-6 3-ethoxysalicylaldehyde 

Relevant articles and documents

Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2?+?2?+?2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi

Rhodium-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulations and nitroalkene reactions have been employed for the synthesis of 56 quinone-based compounds. These were evaluated against Trypanosoma cruzi, the parasite that causes Chagas disease. The reactions described here are part of a program that aims to utilize modern, versatile and efficient synthetic methods for the one or two step preparation of trypanocidal compounds. We have identified 9 compounds with potent activity against the parasite; 3 of these were 30-fold more potent than benznidazole (Bz), a drug used for the treatment of Chagas disease. This article provides a comprehensive outline of reactions involving over 120 compounds aimed at the discovery of new quinone-based frameworks with activity against T. cruzi.

F-labeled PI3K/Akt signal path inhibitor S14161, and preparation method and application thereof

The invention discloses a F-labeled-8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene (S14161) and a preparation method thereof. The preparation method has the following advantages: preparation raw materials are cheap and are easy to obtain, the synthesis process is simple, reaction conditions are mild, and the radiochemical synthesis time is short; the above product is simple and convenient to purify and separate, the radiochemical purity of the product exceeds 98%, the radiochemical yield of the product is high, the uncorrected yield reaches up to 92%, and the radioactivity of the product is high; and the product is useful in the inspection and diagnosis of tumors and the radiation therapy of the tumors. The structural formula of the F-labeled-8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene is shown in the description.