Welcome to LookChem.com Sign In|Join Free

CAS

  • or

207233-90-7

4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate, also known as DIDS, is a chemical compound that acts as a potent inhibitor of anion exchangers and transporters. It is characterized by its ability to bind to specific proteins and inhibit their function, making it a valuable tool in biological research and therapeutic applications.

207233-90-7 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 207233-90-7 Structure

  • Basic information

    1. Product Name: 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&
    2. Synonyms: 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&;4,4'-DIISOTHIOCYANATO-2,2'-STILBENEDISUL -FONIC ACID, DI-NA SALT XH2O TECH., 90%;4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate;4,4''-DIISOTHIOCYANATOSTILBENE-2,2''-DISULPHONIC ACID DISODIUM SALT;4,4μ-Diisothiocyanato-2,2μ-stilbenedisulfonic acid hydrate disodium salt;4,4μ-Diisothiocyanatostilbene-2,2μ-disulfonic acid hydrate disodium salt;DIDS, Disodium 4,4μ-diisothiocyanatostilbene-2,2μ-disulfonate;4,4'-Diisothiocyanatostilbene-2,2'-disulphonic acid disodium salt hydrate
    3. CAS NO:207233-90-7
    4. Molecular Formula: C16H8N2O6S4.2Na
    5. Molecular Weight: 498.491
    6. EINECS: N/A
    7. Product Categories: homoXlink
    8. Mol File: 207233-90-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: yellow/
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Store at 2-8
    8. Solubility: 0.1 M potassium bicarbonate: soluble50mg/mL
    9. BRN: 8179433
    10. CAS DataBase Reference: 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&(207233-90-7)
    12. EPA Substance Registry System: 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&(207233-90-7)

  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 36/37/38-42
    3. Safety Statements: 22-26
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 207233-90-7(Hazardous Substances Data)

207233-90-7 Usage

Uses

Used in Pharmaceutical Research:
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate is used as a band3 protein inhibitor in rabbits for the inhibition of bicarbonate transporters in brain slice tissue. This application aids in understanding the role of bicarbonate transport in various physiological processes and potential therapeutic targets for related disorders.
Used in Embryonic Development Studies:
In the field of embryonic development, 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate is used as an HCO3-/Clexchanger (anion exchanger) in embryos. This helps researchers investigate the role of anion exchange in embryonic development and identify potential targets for therapeutic intervention.
Overall, 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate is a versatile compound with applications in various scientific and medical fields, primarily due to its ability to inhibit specific transporters and exchangers, providing valuable insights into their functions and potential therapeutic uses.

Biochem/physiol Actions

4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles.

Check Digit Verification of cas no

The CAS Registry Mumber 207233-90-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,7,2,3 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 207233-90:
(8*2)+(7*0)+(6*7)+(5*2)+(4*3)+(3*3)+(2*9)+(1*0)=107
107 % 10 = 7
So 207233-90-7 is a valid CAS Registry Number.

207233-90-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name DIDS Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate

1.2 Other means of identification

Product number -
Other names 5-isothiocyanato-2-[2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:207233-90-7 SDS

207233-90-7Upstream product

207233-90-7Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 207233-90-7