207442-39-5

Basic information

• Product Name: 3-[(E)-(3-FLUOROPHENYL)METHYLIDENE]-2,3-DIHYDRO-4H-CHROMEN-4-ONE
• Synonyms: 3-[(E)-(3-FLUOROPHENYL)METHYLIDENE]-2,3-DIHYDRO-4H-CHROMEN-4-ONE
• CAS NO: 207442-39-5
• Molecular Formula: C₁₆H₁₁FO₂
• Molecular Weight: 254.26
• Mol File: 207442-39-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-[(E)-(3-FLUOROPHENYL)METHYLIDENE]-2,3-DIHYDRO-4H-CHROMEN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(E)-(3-FLUOROPHENYL)METHYLIDENE]-2,3-DIHYDRO-4H-CHROMEN-4-ONE(207442-39-5)
• EPA Substance Registry System: 3-[(E)-(3-FLUOROPHENYL)METHYLIDENE]-2,3-DIHYDRO-4H-CHROMEN-4-ONE(207442-39-5)

Safety Data

• Hazardous Substances Data: 207442-39-5(Hazardous Substances Data)

Upstream product

• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 456-48-4 3-Fluorobenzaldehyde 

Relevant articles and documents

Topochemical photodimerization of (E)-3-benzylidene-4-chromanone derivatives from β-type structures directed by halogen groups

Halogen substituent plays an important role in the crystalline packing of aromatic compounds. The [2+2] photocycloaddition of (E)-3-benzylidene-4- chromanones in the crystalline state was investigated, and halogen substitution has been adopted to organize molecules with proper arrangement for photodimerization. Not halogen bonds, but the electron-withdrawing property of halogen atoms can enhance the face-to-face π-π interactions. Therefore, F, Cl or Br substitution at the para position of phenyl gave rise to almost the same β-structures with face-to-face π-stacking. Only resulted β-structures can undergo photodimerization, which gave the syn-HH (syn-head-to-head) products with high regio-/stereoselectivity.