- Benzamide nitriles
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Compounds of the formula (I) wherein m, n, A, R1, R2, R3, R4, R5 and R6 are as described herein, together with methods for making the compounds and using the compounds for treatment of diseases or conditions mediated by Cathepsin K.
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- A general, [1+4] approach to the synthesis of 3(5)-substituted pyrazoles from aldehydes
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A new, one-pot preparation of 3(5)-substituted-1H-pyrazole is described that employs Horner-Emmons reaction of aldehydes with dianion of novel phosphonate 1 and proceeds through cyclization of N-sodium salt of α,β- unsaturated tosylhydrazones 2.
- Almirante, Nicoletta,Cerri, Alberto,Fedrizzi, Giorgio,Marazzi, Giuseppe,Santagostino, Marco
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p. 3287 - 3290
(2007/10/03)
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