20925-31-9 Usage
Uses
Used in Chemical Analysis:
2,3,5,6-TETRAFLUOROPHENYL ISOTHIOCYANATE is used as a derivatization reagent for the analysis of various compounds, including amines and amino acids. It facilitates the formation of spectrophotometrically active substances that can be measured with high precision, enhancing the accuracy and reliability of chemical analysis.
Used in High-Performance Liquid Chromatography (HPLC):
In the field of HPLC, 2,3,5,6-TETRAFLUOROPHENYL ISOTHIOCYANATE is utilized as a derivatization agent to improve the detection and quantification of specific compounds. Its distinctive properties allow for the production of substances with enhanced chromatographic properties, facilitating more efficient separation and analysis.
Used in Pharmaceutical Industry:
2,3,5,6-TETRAFLUOROPHENYL ISOTHIOCYANATE is employed in the pharmaceutical industry for the synthesis of various drugs and active pharmaceutical ingredients. Its reactivity and stability contribute to the development of new compounds with potential therapeutic applications.
Used in Pesticide and Chemical Residue Analysis:
In the area of pesticide and chemical residue analysis, 2,3,5,6-TETRAFLUOROPHENYL ISOTHIOCYANATE serves as a valuable derivatization reagent. It aids in the detection and quantification of trace amounts of pesticides and other chemical residues in various samples, ensuring the safety and quality of food and environmental products.
Check Digit Verification of cas no
The CAS Registry Mumber 20925-31-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,9,2 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 20925-31:
(7*2)+(6*0)+(5*9)+(4*2)+(3*5)+(2*3)+(1*1)=89
89 % 10 = 9
So 20925-31-9 is a valid CAS Registry Number.
InChI:InChI=1/C7HF4NS/c8-3-1-4(9)6(11)7(5(3)10)12-2-13/h1H
20925-31-9Relevant articles and documents
Synthesis and antiinflammatory evaluation of substituted isophthalonitriles, trimesonitriles, benzonitriles, and terephthalonitriles
Heilman,Battershell,Pyne,Goble,Magee
, p. 906 - 913 (2007/10/06)
In an effort to develop nonacidic, nonsteroidal, antiinflammatory agents without gastrointestinal complications, a series of cyanobenzenes was synthesized for antiinflammatory evaluation. Twenty-seven substituted isophthalonitriles, 19 trimesonitriles, 30 benzonitriles, and 16 terephthalonitriles were tested in the rat utilizing the carrageenan-induced pedal edema assay. Based on the performance of phenylbutazone in this assay (43.8% reduction at 100 mg/kg), six compounds, dosed at 50 mg/kg, produced reductions in inflammation comparable to this standard. However, the LD50 value of each compound dosed at this level was in the range of 40-56 mg/kg in the mouse; therefore, further study was not warranted. Fifteen compounds possessed activity in excess of 20% reduction at 200 mg/kg and also possessed LD50 values greater than 300 mg/kg. Of these cyanobenzenes, trimesonitrile, 4-chlorobenzonitrile, 2-chloroterephthalonitrile, and 2-fluoroterephthalonitrile with reductions in edema of 32, 30, 46, and 49%, respectively, represent the best candidates for subsequent study.
