209409-98-3 Usage
Uses
Used in Pharmaceutical Industry:
5-(2,6-DICHLOROPHENYL)-2-PHENYLSULFANYLPYRIDAZINO[6,1-F]PYRIMIDIN-6-ONE is used as a pharmaceutical compound for its potential therapeutic properties. The unique molecular structure of this compound allows it to interact with various biological targets, making it a valuable candidate for the development of new drugs and therapeutic agents.
Used in Drug Discovery and Development:
In the field of drug discovery and development, 5-(2,6-DICHLOROPHENYL)-2-PHENYLSULFANYLPYRIDAZINO[6,1-F]PYRIMIDIN-6-ONE is utilized as a lead compound. Its complex molecular structure and potential pharmaceutical properties make it a valuable starting point for designing and optimizing new drugs with improved efficacy and selectivity.
Used in Medicinal Chemistry Research:
5-(2,6-DICHLOROPHENYL)-2-PHENYLSULFANYLPYRIDAZINO[6,1-F]PYRIMIDIN-6-ONE serves as a subject of study in medicinal chemistry research. Scientists investigate its chemical properties, interactions with biological targets, and potential applications in the treatment of various diseases and conditions.
Used in Chemical Synthesis:
In the field of chemical synthesis, 5-(2,6-DICHLOROPHENYL)-2-PHENYLSULFANYLPYRIDAZINO[6,1-F]PYRIMIDIN-6-ONE is used as a building block or intermediate in the synthesis of more complex molecules with potential pharmaceutical or chemical applications.
Used in Drug Screening and Testing:
5-(2,6-DICHLOROPHENYL)-2-PHENYLSULFANYLPYRIDAZINO[6,1-F]PYRIMIDIN-6-ONE is employed in drug screening and testing processes to evaluate its potential as a therapeutic agent. Researchers assess its efficacy, safety, and mechanism of action in various in vitro and in vivo models to determine its suitability for further development as a drug candidate.
Check Digit Verification of cas no
The CAS Registry Mumber 209409-98-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,4,0 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 209409-98:
(8*2)+(7*0)+(6*9)+(5*4)+(4*0)+(3*9)+(2*9)+(1*8)=143
143 % 10 = 3
So 209409-98-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H11Cl2N3OS/c20-13-7-4-8-14(21)17(13)18-15-9-10-16(23-24(15)11-22-19(18)25)26-12-5-2-1-3-6-12/h1-11H
209409-98-3Relevant articles and documents
The discovery of VX-745: A novel and selective p38α kinase inhibitor
Duffy, John P.,Harrington, Edmund M.,Salituro, Francesco G.,Cochran, John E.,Green, Jeremy,Gao, Huai,Bemis, Guy W.,Evindar, Ghotas,Galullo, Vincent P.,Ford, Pamella J.,Germann, Ursula A.,Wilson, Keith P.,Bellon, Steven F.,Chen, Guanging,Taslimi, Paul,Jones, Peter,Huang, Cassey,Pazhanisamy,Wang, Yow-Ming,Murcko, Mark A.,Su, Michael S.S.
supporting information; experimental part, p. 758 - 763 (2011/12/03)
The synthesis of novel, selective, orally active 2,5-disubstituted 6H-pyrimido[1,6-b]pyridazin-6-one p38α inhibitors is described. Application of structural information from enzyme-ligand complexes guided the selection of screening compounds, leading to t
An improved synthesis of 5-(2,6-dichlorophenyl)-2-(phenylthio)-6H- pyrimido[1,6-b]pyridazin-6-one (a VX-745 analog)
Treu, Matthias,Jordis, Ulrich,Lee, Ving J.
, p. 959 - 963 (2007/10/03)
An improved procedure for the synthesis an analog of the p38 inhibitor compound VX-745 is reported.