Enantioselective syntheses of trans-3,4-difluoropyrrolidines and investigation of their applications in catalytic asymmetric synthesis
Asymmetric syntheses of enantiopure trans-3,4-difluoropyrrolidines have been prepared by the introduction of fluorine at both centers in a single operation; asymmetric epoxidations and additions to benzaldehyde were conducted using catalysts whose chirality depends on organofluorine asymmetry.
Marson, Charles M.,Melling, Robert C.
p. 9771 - 9779
(2007/10/03)
The first enantioselective syntheses of vicinal difluoropyrrolidines and the first catalytic asymmetric synthesis mediated by the C2 symmetry of a -CHFCHF- Unit
The first enantiopure vicinal difluorides of C2 symmetry have been prepared by the introduction of fluorine at both centres in a single operation; the first asymmetric synthesis using a catalyst whose chirality depends on organofluorine asymmetry is described.
Marson, Charles M.,Melling, Robert C.
p. 1223 - 1224
(2007/10/03)
More Articles about upstream products of 209625-77-4