209679-21-0 Usage
Uses
Used in Pharmaceutical Industry:
(R)-3-(4-FLUOROPHENYL)BUTANOIC ACID is used as an intermediate in the synthesis of pharmaceuticals for its ability to interact with biological systems. Its chiral nature and specific interactions with biological targets make it a promising candidate for the development of new drugs and medications.
Used in Drug Development:
(R)-3-(4-FLUOROPHENYL)BUTANOIC ACID is used as a building block in the development of new drugs, as its structure can be modified to create compounds with specific therapeutic properties. Its ability to interact with biological systems allows researchers to design and synthesize novel drug candidates with potential applications in various therapeutic areas.
Used in Medicinal Chemistry Research:
(R)-3-(4-FLUOROPHENYL)BUTANOIC ACID is used as a research tool in medicinal chemistry to study the structure-activity relationships of biologically active compounds. Its chiral nature and ability to interact with specific biological targets make it a valuable compound for understanding the mechanisms of drug action and for optimizing the design of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 209679-21-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,6,7 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 209679-21:
(8*2)+(7*0)+(6*9)+(5*6)+(4*7)+(3*9)+(2*2)+(1*1)=160
160 % 10 = 0
So 209679-21-0 is a valid CAS Registry Number.
209679-21-0Relevant articles and documents
Two-carbon ring expansion of 1-indanones via insertion of ethylene into carbon-carbon bonds
Xia, Ying,Ochi, Shusuke,Dong, Guangbin
, p. 13038 - 13042 (2019/08/26)
A rhodium-catalyzed direct insertion of ethylene into a relatively unstrained carbon-carbon bond in 1-indanones is reported, which provides a two-carbon ring expansion strategy for preparing seven-membered cyclic ketones. As many 1-indanones are commercially available and ethylene is inexpensive, this strategy simplifies synthesis of benzocycloheptenones that are valuable synthetic intermediates for bioactive compounds but challenging to prepare otherwise. In addition, the reaction is byproduct-free, redox neutral, and tolerant of a wide range of functional groups, which may have implications on unconventional strategic bond disconnections for preparing complex cyclic molecules.
Lipase catalysed kinetic resolutions of 3-aryl alkanoic acids
Deasy, Rebecca E.,Brossat, Maude,Moody, Thomas S.,Maguire, Anita R.
, p. 47 - 61 (2011/04/18)
Hydrolase catalysed kinetic resolutions leading to a series of 3-aryl alkanoic acids (≥94% ee) are described. Hydrolysis of the ethyl esters with a series of hydrolases was undertaken to identify biocatalysts that yield the corresponding acids with excellent enantiopurity in each case. Steric and electronic effects on the efficiency and enantioselectivity of the biocatalytic transformation were also explored.
