21039-72-5Relevant articles and documents
Tert -Butyl nitrite (TBN) as the N atom source for the synthesis of substituted cinnolines with 2-vinylanilines and a relevant mechanism was studied
Pang, Xiaobo,Zhao, Lianbiao,Zhou, Dagang,He, Ping Yong,An, Zhenyu,Ni, Ji Xiang,Yan, Rulong
, p. 6318 - 6322 (2017/08/10)
A green method to synthesize cinnolines by 6π electrocyclic reaction with alkenyl amines and TBN has been developed. TBN plays a dual role both as a nitrogen atom source and an oxidant in this procedure. Relevant mechanism experiments reveal that the reaction proceeds through electrocyclic reaction and with diazo hydroxide as a key intermediate.