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CAS

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21041-10-1

Dihydronarwedine, a metabolite of Galanthamine (G188500), is a bioactive compound with significant therapeutic potential. It functions as a selective acetylcholinesterase inhibitor, playing a crucial role in the treatment and prevention of Alzheimer's disease and other disorders stemming from reduced neuronal metabolism. Its ability to modulate cholinergic neurotransmission makes it a valuable compound in the realm of neurodegenerative disease management.

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  • 21041-10-1 Structure

  • Basic information

    1. Product Name: Dihydronarwedine
    2. Synonyms: Dihydronarwedine;Dihydro GalantaMinone HCl
    3. CAS NO:21041-10-1
    4. Molecular Formula: C17H21NO3
    5. Molecular Weight: 287.35354
    6. EINECS: N/A
    7. Product Categories: Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 21041-10-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Dihydronarwedine(CAS DataBase Reference)
    10. NIST Chemistry Reference: Dihydronarwedine(21041-10-1)
    11. EPA Substance Registry System: Dihydronarwedine(21041-10-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 21041-10-1(Hazardous Substances Data)

21041-10-1 Usage

Uses

Used in Pharmaceutical Industry:
Dihydronarwedine is used as a therapeutic agent for the treatment and prevention of Alzheimer's disease. Its selective inhibition of acetylcholinesterase helps to enhance cognitive function and memory by increasing the levels of acetylcholine in the brain, thereby improving neuronal communication and overall brain health.
Used in Neurodegenerative Disorder Management:
Dihydronarwedine is utilized as a neuroprotective agent for the management of disorders resulting from reduced neuronal metabolism. Its role in maintaining acetylcholine levels contributes to the preservation of neuronal integrity and function, offering potential benefits for patients suffering from various neurodegenerative conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 21041-10-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,0,4 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21041-10:
(7*2)+(6*1)+(5*0)+(4*4)+(3*1)+(2*1)+(1*0)=41
41 % 10 = 1
So 21041-10-1 is a valid CAS Registry Number.

21041-10-1Upstream product

21041-10-1Relevant articles and documents

Total synthesis of (±)-Galanthamine via a C3-selective stille coupling and IMDA cycloaddition cascade of 3,5-dibromo-2-pyrone

Chang, Jay Hyok,Kang, Ho-Ung,Jung, In-Hak,Cho, Cheon-Gyu

supporting information; experimental part, p. 2016 - 2018 (2010/06/21)

Figure presented A new efficient synthetic route to (±)-galanthamine was devised by using a tandem C3-selective Stille coupling-IMDA cascade of 3,5-dibromo-2-pyrone as a key strategy.

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