Methyl-3-O-(2-acetamido-2-deoxy-6-thio-β-D-glucopyranosyl)-β-D-galactopyranoside: a slow reacting acceptor-analogue which inhibits glycosylation by UDP-D-galactose-N-acetyl-D-glucosamine-(1->4)-β-D-galactosyltransferase
Novel features of acceptor recognition by β-(1 ← 4)- galactosyltransferase
In order to understand how β-(1→4)-galactosyltransferase recognizes its glycosyl acceptor, substrate specificities were investigated using synthetic 2-acetamido-2-deoxy-D-glucopyranose (N-acetylglucosamine) derivatives in which the 1-, 2-, 3-, 4-, and 6-p