210538-68-4

Basic information

• Product Name: 5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE
• Synonyms: 5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE;5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine monohydrochloride;5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine HCl
• CAS NO: 210538-68-4
• Molecular Formula: C7H10ClN3
• Molecular Weight: 171.6274
• Product Categories: pyrimidine;Heterocycle-Pyrimidine series
• Mol File: 210538-68-4.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE(210538-68-4)
• EPA Substance Registry System: 5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE(210538-68-4)

Safety Data

• Hazardous Substances Data: 210538-68-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE is used as a key component in the development of new drugs due to its potential therapeutic effects. Its unique chemical structure allows for the exploration of various drug candidates targeting different diseases and conditions.
Used in the Treatment of Neurological Disorders:
In the field of neurology, 5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE is used as a potential therapeutic agent for the treatment of various neurological disorders. Its ability to modulate specific biological pathways and interact with cellular targets makes it a promising candidate for the development of novel treatments.
Used in Cancer Therapy:
5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE is also used in cancer research and treatment. It has been studied for its potential to target cancer cells, inhibit tumor growth, and enhance the effectiveness of existing cancer therapies. Its unique chemical properties allow for the development of targeted drug delivery systems, improving the efficacy and reducing the side effects of cancer treatments.
Used in Medicinal Chemistry:
As an important chemical for medicinal chemistry, 5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDINE HYDROCHLORIDE is used in the synthesis of various drug candidates and the exploration of new chemical entities. Its versatile structure enables the development of compounds with diverse biological activities, contributing to the advancement of pharmaceutical research.

Upstream product

• 157327-41-8 t-butyl-3-[(dimethylamino)methylidene]-4-oxopiperidine-1-carboxylate 
• 3473-63-0 formamidine acetic acid 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Relevant articles and documents

Synthesis of the bicyclic secondary amines via dimethylaminomethylene ketones from 3-pyrrolidone and 4-piperidone

The reaction of N-protected 3-pyrrolidone and 4-piperidone with N,N-dimethylformamide dimethyl acetal gave the dimethylaminomethylene ketones, which reacted with several types of hydrazines, amidines, and guanidine to afford the secondary amines having fused ring system.

Quinoline and quinazoline compounds useful in therapy, particularly in the treatment of benign prostatic hyperplasia

Compounds of formula I, STR1whereinR 1 represents C 1-4 alkoxy optionally substituted by one or more fluorine atoms;R 2 represents H or C 1-6 alkoxy optionally substituted by one or more fluorine atoms;R 3 represents a 5- or 6-membered heterocyclic ring, the ring being optionally substituted;R 4 represents a 4-, 5-, 6-, or 7-membered heterocyclic ring, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring, the ring system as a whole being optionally substituted;X represents CH or N; andL is absent,or represents a cyclic group of formula Ia, STR2or represents a chain of formula Ib, STR3and pharmaceutically acceptable salts thereof, are useful in therapy, in particular in the treatment of benign prostatic hyperplasia.