211508-95-1

Basic information

• Product Name: 2-ETHYNYLBENZYL BROMIDE
• Synonyms: 2-ETHYNYLBENZYL BROMIDE
• CAS NO: 211508-95-1
• Molecular Formula: C₉H₇Br
• Molecular Weight: 195.05588
• Mol File: 211508-95-1.mol

Chemical Properties

• Boiling Point: 246.8±23.0 °C(Predicted)
• Appearance: /
• Density: 1.42±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-ETHYNYLBENZYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYNYLBENZYL BROMIDE(211508-95-1)
• EPA Substance Registry System: 2-ETHYNYLBENZYL BROMIDE(211508-95-1)

Safety Data

• Hazardous Substances Data: 211508-95-1(Hazardous Substances Data)

Upstream product

• 10602-08-1 2-ethynylbenzyl alcohol 
• 5159-41-1 2-iodobenzyl alcohol 
• 89-95-2 2-methyl-benzyl alcohol 
• 229027-92-3 {2-[2-(trimethylsilyl)ethynyl]phenyl}methanol 
• 442904-02-1 {[2-(bromomethyl)phenyl]ethynyl}trimethylsilane 

Downstream Products

• 220798-69-6 (2-ethynyl-phenyl)-methaneselenol 
• 134079-25-7 1-<2-(Bromomethyl)phenyl>vinyl bromide 
• 1187458-53-2 2-allyl-2-(2-ethynyl-benzyl)-malonic acid diethyl ester 
• 1187458-67-8 2-((E)-3,7-dimethylocta-2,6-dienyl)-2-(2-ethynyl-benzyl)malonic acid dimethyl ester 
• 1187458-51-0 2-(2-ethynyl-benzyl)-2-(2-methyl-allyl)-malonic acid dimethyl ester 
• 1194059-97-6 (Z)-dimethyl 2-(2-ethynylbenzyl)-2-(3-methylpent-2-en-4-ynyl)malonate 
• 1194059-98-7 dimethyl 2-(2-ethynylbenzyl)-2-((2-ethynylcyclohex-1-enyl)methyl)malonate 
• 1194059-99-8 dimethyl 2-(2-ethynylbenzyl)-2-((2-ethynylcyclopent-1-enyl)methyl)malonate 
• 1194060-00-8 dimethyl 2-(2-ethynylbenzyl)-2-(pent-4-ynyl)malonate 
• 1194059-89-6 dimethyl 2,2-bis(2-ethynylbenzyl)malonate 
• 1254181-49-1 o-ethynylbenzylphenylselenide 
• 1427302-19-9 C₂₀H₂₀O 
• 1427302-31-5 C₁₉H₂₆O 

Relevant articles and documents

Pd(0)-catalyzed [1,5]-sigmatropic hydrogen shift of propargylic esters toward substituent naphthylamines

A novel and convenient carboannulation method for the synthesis of highly substituted naphthylamine derivatives has been developed though a Pd(0)-catalyzed [1,5]-sigmatropic hydrogen shift and cyclization reaction of propargyl esters.

An unusual access to medium sized cycloalkynes by a new goId(I)-catalysed cycloisomerisation of diynes

A study was conducted to demonstrate efficient cycloisomerization of a series of 1,9- and 1,10-diynes into medium sized cycloalkynes by a gold-catalyzed alkyne-alkyne coupling. The reaction was performed using 4 mol% of gold complex in CD2Cl2 at room temperature and was monitored by using 1H NMR spectroscopy. The reaction of analogous diyne substrate was more rapid and a complete conversion was observed after 40 hours at room temperature. The cycloalkyne was isolated as a solid in 95% yield from which single crystals suitable for X-ray crystal structure determination was obtained. A rapid screening of catalysts and experimental conditions was undertaken to optimize the formation of cycloalkyne. A mechanistic proposal was also introduced for the cycloisomerization of diynes into cycloalkynes on the basis of the experimental observations.

Free radical-mediated vinyl amination: A mild, general pyrrolidinyl enamine synthesis

The complete scope of free radical-mediated vinyl amination is described, using 5-exo-trig cyclizations of vinyl radicals to the nitrogen of azomethines. The focus is primarily on N,N-dialkyl enamines since their nucleophilicity renders them the most challenging enamines to synthesize using redox conditions. These studies establish several encouraging precedents for the broader application of this strategy.

Studies on tellurium-containing heterocycles. Part 18. Preparation and structure of 2-benzotelluropyrylium salts and 2-benzoselenopyrylium salts

The regioselective and stereospecific intramolecular ring closure reactions of o-ethynylbenzyl tellurols 5A and o-ethynylbenzyl selenols 5B, which were readily generated by the reaction of the o-ethynylbenzyl bromides 4 with sodium hydrogen telluride (NaH