211915-66-1

Basic information

• Product Name: 5-Benzothiazolecarboxylicacid,2-(methoxymethyl)-(9CI)
• Synonyms: 5-Benzothiazolecarboxylicacid,2-(methoxymethyl)-(9CI)
• CAS NO: 211915-66-1
• Molecular Formula: C₁₀H₉NO₃S
• Molecular Weight: 223.24836
• Product Categories: BENZOTHIAZOLE
• Mol File: 211915-66-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Benzothiazolecarboxylicacid,2-(methoxymethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzothiazolecarboxylicacid,2-(methoxymethyl)-(9CI)(211915-66-1)
• EPA Substance Registry System: 5-Benzothiazolecarboxylicacid,2-(methoxymethyl)-(9CI)(211915-66-1)

Safety Data

• Hazardous Substances Data: 211915-66-1(Hazardous Substances Data)

Upstream product

• 211915-65-0 2-methoxymethylbenzothiazole-5-carboxylic acid ethyl ester 
• 455-75-4 ethyl 3-amino-4-fluorobenzoate 
• 211915-64-9 ethyl 4-fluoro-3-methoxyacetylaminobenzoate 

Downstream Products

• 211915-67-2 2-methoxymethyl-benzothiazole-5-carboxylic acid-N-phenyl-N-(2-ethoxycarbonylethyl)-amide 
• 211915-68-3 2-[N-(4-cyanophenyl)-aminomethyl]-benzothiazole-5-carboxylic acid-N-phenyl-N-(2-ethoxycarbonylethyl)-amide 
• 211914-01-1 2-[N-(4-amidinophenyl)-aminomethyl]-benzothiazole-5-carboxylic acid-N-phenyl-N-(2-ethoxycarbonylethyl)-amide 
• 211914-02-2 2-[N-(4-amidinophenyl)-aminomethyl]-benzthiazole-5-carboxylic acid-N-phenyl-N-(2-carboxyethyl)-amide 

Relevant articles and documents

Multi-substituted 4-methyl ester derivative of amino benzonitrile trunk and its preparation and use

The invention provides new ester derivatives with a general formula (I) shown in the specification of multi-substituted 4-methylamino-benzamidine or pharmaceutically acceptable salts, wherein A1, A2, A3 and A4 in the formula are as defined in the specification. The compounds have an anticoagulant effect and can be used for preparing medicaments for preventing and treating thromboembolic diseases.

Disubstituted bicyclic heterocycles, the preparations and the use thereof as pharmaceutical compositions

New disubstituted bicyclic heterocycles of general formula Ra-A-Het-B-Ar-E (I)Compounds of the above general formula I, wherein E denotes an RbNH-C(=NH)- group, have valuable pharmacological properties, particularly a thrombin-inhibiting effect and the effect of prolonging thrombin time, and those wherein E denotes a cyano group, are valuable intermediates for preparing the other compounds of general formula I. Exemplary compounds of formula I are: (a) 1-Methyl-2-[N-(4-amidinophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-phenyl-N-(2-hydroxycarbonylethyl)-amide, (b) 1-Methyl-2-[N-(4-amidinophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(hydroxycarbonylmethyl)-amide, (c) 1-Methyl-2-[N-(4-amidino-2-methoxy-phenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(hydroxycarbonylmethyl)-amide, and (d) 1-Methyl-2-[N-[4-(N-n-hexyloxycarbonylamidino)phenyl]aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl) amide.