- Targeting DNA binding for NF-κB as an anticancer approach in hepatocellular carcinoma
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Quinoline core has been shown to possess a promising role in the development of anticancer agents. However, the correlation between its broad spectrum of bioactivity and the underlying mechanism of actions is poorly understood. The present study, with the
- Chung, Po-Yee,Lam, Pik-Ling,Zhou, Yuan-Yuan,Gasparello, Jessica,Finotti, Alessia,Chilin, Adriana,Marzaro, Giovanni,Gambari, Roberto,Bian, Zhao-Xiang,Kwok, Wai-Ming,Wong, Wai-Yeung,Wang, Xi,Lam, Alfred King-Yin,Chan, Albert Sun-Chi,Li, Xingshu,Ma, Jessica Yuen-Wuen,Chui, Chung-Hin,Lam, Kim-Hung,Tang, Johnny Cheuk-On
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- COMPOUND, COLOR MATERIAL COMPOSITION CONTAINING THE SAME, AND RESIN COMPOSITION CONTAINING THE SAME
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PROBLEM TO BE SOLVED: To provide a novel compound, a color material composition containing the same and a resin composition containing the same that improve the color purity, luminance and contrast ratio in color filter production employing a pigment dispersion method using pigments. SOLUTION: The invention provides a compound represented by the chemical formula 1, a color material composition containing the same, and a resin composition containing the same. (Y is a direct bond or CQ1Q2; R1-R14, Q1 and Q2 are each independently H, D, or a halogen group, nitrile group, nitro group, hydroxy group, carbonyl group, ester group, imide group, amide group, carboxy group (-COOH), or -OC(=O)R'''; and the like.) SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2017,JPOandINPIT
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Paragraph 0171-0173
(2017/07/13)
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- Evaluation of some quinoline-based hydrazone derivatives as insecticidal agents
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In continuation of our program aimed at the discovery and development of efficient insecticidal agents, a series of quinoline-based hydrazone derivatives were synthesized and evaluated as insecticidal agents against three-day-old larvae of Spodoptera litura (Noctuidae: Lepidoptera), a polyphagous insect pest of many important crops, in vivo at 1 mg mL1. In particular, compounds 3c, 3e, 4g, 4h, and 6f showed potent insecticidal activity with 7 day mortality rates greater than 93%, and were comparable to that of the positive control toosendanin.
- Yu, Xiang,Feng, Gang,Huang, Jiulin,Xu, Hui
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p. 30405 - 30411
(2019/01/14)
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- Photochemical cleavage reactions of 8-quinolinyl sulfonates in aqueous solution
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Photochemical cleavage reactions of 8-quinolinyl benzenesulfonate derivatives and related sulfonates in aqueous solutions are reported. The 8-quinolinyl benzenesulfonates undergo photolysis upon photoirradiation at 300-330 nm to give the corresponding 8-quinolinols and benzenesulfonic acids with the production of only negligible amounts of byproducts. The effects of substituent groups of the 8-quinolinyl moiety and the benzene ring on the photolysis reactions were examined. Based on steady-state mechanistic studies using a triplet sensitizer, a triplet quencher, and electron donors, it was suggested that the photolysis proceeds mainly via the homolytic cleavage of S-O bonds in the excited triplet state.
- Kageyama, Yoshiyuki,Ohshima, Ryosuke,Sakurama, Kazusa,Fujiwara, Yoshihisa,Tanimoto, Yoshifumi,Yamada, Yasuyuki,Aoki, Shin
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experimental part
p. 1257 - 1266
(2010/05/02)
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