Design and synthesis of novel xanthine derivatives as potent and selective A2B adenosine receptor antagonists for the treatment of chronic inflammatory airway diseases
Adenosine induces bronchial hyperresponsiveness and inflammation in asthmatics through activation of A2B adenosine receptor (A2BAdoR). Selective antagonists have been shown to attenuate airway reactivity and improve inflammatory cond
Model studies of (+)-Bergenin: A convenient formation of aryl δ- lactones
The reaction of o-carboxyarylpropargyl bromides with aldehydes mediated by indium in aqueous medium conveniently generated aryl δ-lactones. The product formation was affected by the nature of the co-solvent.
Hua, Xiao-Gang,Mague, Joel T.,Li, Chao-Jun
p. 6837 - 6840
(2007/10/03)
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