214540-43-9 Usage
Type of compound
Heterocyclic compound with a triazole ring
Uses
Building block for the synthesis of biologically active compounds and drugs in the pharmaceutical industry; research tool for studying structure-activity relationships of biological targets
Specific properties
Benzyl group and bromine and fluorine atoms attached to the triazole ring confer specific properties to the compound, making it useful in medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 214540-43-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,4,5,4 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 214540-43:
(8*2)+(7*1)+(6*4)+(5*5)+(4*4)+(3*0)+(2*4)+(1*3)=99
99 % 10 = 9
So 214540-43-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H7BrFN3/c10-8-12-9(11)14(13-8)6-7-4-2-1-3-5-7/h1-5H,6H2
214540-43-9Relevant articles and documents
The first versatile synthesis of 1-alkyl-3-fluoro-1H-[1,2,4]triazoles
Zumbrunn, Albrecht
, p. 1357 - 1361 (2007/10/03)
Reaction of 1-benzyl-3,5-dibromo-1H-[1,2,4]triazole (3) with cesium fluoride yielded selectively 1-benzyl-3-bromo-5-fluoro-1H-[1,2,4]triazole (4). Debenzylation and realkylation afforded 1-alkyl-5-bromo-3-fluoro-1H-[1,2,4]triazoles 7, which reacted with a wide variety of nucleophiles to give 5-substituted 1-alkyl-3-fluoro-1H-[1,2,4]triazoles.
