214554-43-5

Basic information

• Product Name: 5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON)
• Synonyms: 5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON);N-Acetyl4-(dipyrrol-2-yl)methylaniline;5-(4-Acetamidophenyl)dipyrromethane
• CAS NO: 214554-43-5
• Molecular Formula: C₁₇H₁₇N₃O
• Molecular Weight: 279.33638
• Product Categories: Porphyrins
• Mol File: 214554-43-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON)(214554-43-5)
• EPA Substance Registry System: 5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON)(214554-43-5)

Safety Data

• Hazardous Substances Data: 214554-43-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON) is used as a key intermediate in various organic synthesis reactions. Its unique structure allows for the formation of a wide range of compounds, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Catalytic Processes:
5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON) is also used in catalytic processes, where it can act as a catalyst or a ligand to enhance the efficiency and selectivity of various chemical reactions. Its stability under argon makes it an ideal candidate for use in sensitive catalytic systems that require an inert atmosphere.
Used in Research and Development:
5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON) is used in research and development laboratories to explore new chemical reactions and develop innovative synthetic methods. Its unique properties and stability under argon make it an attractive candidate for studying reaction mechanisms and developing new catalytic systems.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON) is used as a starting material or intermediate in the synthesis of various drug candidates. Its versatility in organic synthesis allows for the development of new and improved pharmaceutical compounds with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, 5-(4-ACETAMIDOPHENYL)DIPYRROMETHANE (UNDER ARGON) is used in the synthesis of various agrochemicals, such as pesticides and herbicides. Its unique structure and reactivity make it a valuable building block for the development of new and more effective agrochemical products.

Upstream product

• 109-97-7 pyrrole 
• 122-85-0 para-acetamidobenzaldehyde 

Downstream Products

• 1345115-43-6 C₆₀H₆₇N₅O₅Zn 

Relevant articles and documents

Synthesis, structure, photophysical, electrochemical properties and antibacterial activity of brominated BODIPYs as an inhibitor of DNA gyrase B of S. aureus

BODIPYs with 3-thienyl and 4-acetamido phenyl groups substituted at the meso-position are subjected to regioselective bromination using three equivalents of N-bromosuccinimide (NBS) to yield their 2-mono and 2,6-di bromoderivatives. Their photophysical, e

Compositions and methods for treating cancer

The invention features compositions and methods for treating or alleviating a symptom of cancer. The compositions and methods of the invention direct supra-lethal doses of radiation, called Hot-Spots, to virtually all cancer cell types.

Chromophores

The present invention relates to novel porphyrin and porphyrin-based chromophores and sets of porphyrin and porphyrin-based chromophores, which may be particularly useful in a range of photodynamic applications, including photochemotherapy and fluorescence analysis and imaging. In particular, the present invention provides new and useful porphyrin, chlorin and bacteriochlorin chromophores; methods for the production of such chromophores; and methods for the use of such chromophores in analysis and in medicine.

Rational Syntheses of Porphyrins Bearing up to Four Different Meso Substituents

Porphyrins bearing specific patterns of substituents are crucial building blocks in biomimetic and materials chemistry. We have developed methodology that avoids statistical reactions, employs minimal chromatography, and affords up to gram quantities of regioisomerically pure porphyrins bearing predesignated patterns of up to four different meso substituents. The methodology is based upon the availability of multigram quantities of dipyrromethanes. A procedure for the diacylation of dipyrromethanes using EtMgBr and an acid chloride has been refined. A new procedure for the preparation of unsymmetrical diacyl dipyrromethanes has been developed that involves (1) monoacylation with EtMgBr and a pyridyl benzothioate followed by (2) introduction of the second acyl unit upon reaction with EtMgBr and an acid chloride. The scope of these acylation methods has been examined by preparing multigram quantities of diacyl dipyrromethanes bearing a variety of substituents. Reduction of the diacyl dipyrromethane to the corresponding dipyrromethane-dicarbinol is achieved with NaBH4 in methanolic THF. Porphyrin formation involves the acid-catalyzed condensation of a dipyrromethane-dicarbinol and a dipyrromethane followed by oxidation with DDQ. Optimal conditions for the condensation were identified after examining various reaction parameters (solvent, temperature, acid, concentration, time). The conditions identified (2.5 mM reactants in acetonitrile containing 30 mM TFA at room temperature for 3B, trans-A2B2, trans-AB2C, cis-A2B2, cis-A2BC, and ABCD were prepared, including >1-g quantities of three porphyrins.