21478-01-3 Usage
Uses
Used in Pharmaceutical Industry:
[R-(R,R)]-2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulphonyl)phenyl]propyl palmitate is used as an anti-inflammatory agent for its ability to reduce inflammation, which is a common characteristic of various diseases and conditions. Its application aims to alleviate the symptoms and provide relief to patients suffering from inflammatory disorders.
[R-(R,R)]-2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulphonyl)phenyl]propyl palmitate is also used as an analgesic agent due to its pain-relieving properties. This makes it a valuable component in the development of medications aimed at treating pain-related conditions, offering an alternative to conventional pain management therapies.
Additionally, given its structural complexity and the presence of multiple functional groups, this compound may have potential applications in other areas of pharmaceutical research, such as drug delivery systems or targeted therapies. However, further investigation and development would be necessary to explore these possibilities fully.
Check Digit Verification of cas no
The CAS Registry Mumber 21478-01-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,7 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21478-01:
(7*2)+(6*1)+(5*4)+(4*7)+(3*8)+(2*0)+(1*1)=93
93 % 10 = 3
So 21478-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C28H45Cl2NO6S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(32)37-21-24(31-28(34)27(29)30)26(33)22-17-19-23(20-18-22)38(2,35)36/h17-20,24,26-27,33H,3-16,21H2,1-2H3,(H,31,34)
21478-01-3Relevant articles and documents
Regioselective preparation of thiamphenicol esters through lipase-catalyzed processes
Da Silva, Marcos R.,Montenegro, Tasso G.C.,De Mattos, Marcos C.,De Oliveira, Maria Da Conceic?a?o F.,De Lemos, Telma L.G.,De Gonzalo, Gonzalo,Lavandera, Iva?n,Gotor-Ferna?ndez, Vicente,Gotor, Vicente
, p. 987 - 994 (2014/07/07)
The lipase-catalyzed synthesis of thiamphenicol derivatives has been studied through complementary acylation and hydrolytic approaches, finding Candida antarctica lipase B as the most efficient biocatalyst for the selective modification of both thiampheni
Synthesis of Ester Derivatives of Chloramphenicol by Lipase-Catalyzed Transesterification in Organic Solvents
Ottolina, Gianluca,Carrea, Giacomo,Riva, Sergio
, p. 2366 - 2369 (2007/10/02)
Regioselective esterification of chloramphenicol (1) and its synthetic analogue thiamphenicol (2) has been achieved by the action of lipase in acetone and several methyl carboxylates.Aliphatic and aromatic esters of different sizes and natures have been introduced selectively on the primary hydroxyl group of these molecules by modification of the reaction conditions (e.g., temperature, solvent, and lipase source).
