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2-(2-chlorophenyl)iMidazole[4,5f][1,10]phenanthroline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 215601-93-7 Structure
  • Basic information

    1. Product Name: 2-(2-chlorophenyl)iMidazole[4,5f][1,10]phenanthroline
    2. Synonyms: 2-(2-chlorophenyl)iMidazole[4,5f][1,10]phenanthroline;2-(2-chlorophenyl)-1H-imidazo[4,5f][1,10]phenanthroline
    3. CAS NO:215601-93-7
    4. Molecular Formula: C19H11ClN4
    5. Molecular Weight: 330.77
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 215601-93-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(2-chlorophenyl)iMidazole[4,5f][1,10]phenanthroline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(2-chlorophenyl)iMidazole[4,5f][1,10]phenanthroline(215601-93-7)
    11. EPA Substance Registry System: 2-(2-chlorophenyl)iMidazole[4,5f][1,10]phenanthroline(215601-93-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 215601-93-7(Hazardous Substances Data)

215601-93-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 215601-93-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,6,0 and 1 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 215601-93:
(8*2)+(7*1)+(6*5)+(5*6)+(4*0)+(3*1)+(2*9)+(1*3)=107
107 % 10 = 7
So 215601-93-7 is a valid CAS Registry Number.

215601-93-7Relevant articles and documents

Luminescent ruthenium(II)-para-cymene complexes of aryl substituted imidazo-1,10-phenanthroline as anticancer agents and the effect of remote substituents on cytotoxic activities

Ashok Kumar, S. K.,Banerjee, Subhasis,De, Sourav,Gauthaman, Ashna,Moorthy, Anbalagan,Paira, Priyankar,Selva Kumar, R.

, (2020/10/18)

Ruthenium complexes are currently significant attention in medicinal chemistry as they offer various properties which make them an appropriate choice for drug development. Herein, a series of ruthenium(II)-p-cymene-2-aryl-imidazo-1,10-phenanthroline derivatives have been prepared and characterised by elemental analysis, infrared, LC-mass and NMR techniques. The structural and chemical properties shows that Ru(II) complexes have got rigidity, planarity, aromaticity, hydrogen donating and accepting capability which aids both solubility and interaction with biomolecules. The binding strength of these complexes with DNA and BSA were found to be 104–106 M?1. The competitive displacement of ethidium bromide (EtBr) from DNA in the presence of complex reveals an intercalation or groove binding further this was supported by viscosity and in-silico studies. The cytotoxicity study of these Ru(II) complexes were conducted with two cancer cell lines (MDA-MB-231 and HeLa) and one human embryonic kidney cells (HEK-293). The study revealed that [(η6-p-cymene)RuCl (κ2-N,N-2-(4-fluorophenyl)-1H-imidazo[4,5-f][1,10]Phenanthroline].PF6 (4e), [(η6-p-cymene)RuCl(κ2-N,N-2-(4-bromophenyl)-1H-imidazo[4,5-f][1,10]Phenanthroline].PF6 (4f) and [(η6-p-cymene)RuCl(κ2-N,N-2-(4-nitrophenyl)-1H-imidazo[4,5-f][1,10]Phenanthro line].PF6 (4g) were found exhibit least inhibitory concentration (IC50) and high selectivity with respect to HeLa and MDA-MB-231. The activity of the Ru(II) complexes were position and substituents dependent.

Arene ruthenium(ii) complexes induce S-phase arrest in MG-63 cells through stabilization of c-Myc G-quadruplex DNA

Fan, Cundong,Wu, Qiong,Chen, Tianfeng,Zhang, Yibo,Zheng, Wenjie,Wang, Qi,Mei, Wenjie

supporting information, p. 597 - 602 (2014/05/06)

A series of arene ruthenium(ii) complexes coordinated by phenanthroimidazole derivatives have been synthesized and evaluated for their in vitro anticancer activities. It has been found that these types of arene Ru(ii) complexes, especially [(C6

Microwave-assisted synthesis of arene ruthenium(ii) complex as apoptosis inducer of A549 cells

Wu, Qiong,Wu, Jian,Mei, Wen-Jie,Wang, Qi,Zhang, Zhao,Wu, Xiao-Hui,Sun, Fen-Yong,Wu, Wei-Li,Chen, Yan-Hua,Hu, Xiao-Ying,Tao, Yun-Yi

, p. 1422 - 1427 (2013/12/04)

An arene ruthenium(ii) complex coordinated with 2-(2-chlorophenyl)-1H- imidazo[4,5-f][1,10]phenanthroline, [(η6-C6H6)Ru(o-ClPIP)Cl]Cl (1), has been prepared by using microwave-assisted synthesis technology. The anti-tumour activity of this complex against

Interaction of Polypyridyl Ruthenium(II) Complexes Containing Non-Planar Ligands with DNA

Xiong, Ya,He, Xiao-Feng,Zou, Xiao-Hua,Wu, Jian-Zhong,Chen, Xiao-Ming,et al.

, p. 19 - 24 (2007/10/03)

2-(2-Chlorophenyl)imidazo1,10-phenanthroline (CIP) or 2-(2-nitrophenyl)imidazo1,10-phenanthroline (NIP) and their complexes 2+ and 2+ (bpy = 2,2'-bipyridine) have been synthesized and chara

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