215867-32-6Relevant articles and documents
Synthesis and pharmacological characterization of 4-substituted-2- aminobicyclo[3.1.0]hexane-2,6-dicarboxylates: Identification of new potent and selective metabotropic glutamate 2/3 receptor agonists
Monn, James A.,Valli, Matthew J.,Massey, Steven M.,Hao, Junliang,Reinhard, Matthew R.,Bures, Mark G.,Heinz, Beverly A.,Wang, Xushan,Carter, Joan H.,Getman, Brian G.,Stephenson, Gregory A.,Herin, Marc,Catlow, John T.,Swanson, Steven,Johnson, Bryan G.,McKinzie, David L.,Henry, Steven S.
, p. 4442 - 4455 (2013/07/19)
As part of our ongoing interest in identifying novel agonists acting at metabotropic glutamate (mGlu) 2/3 receptors, we have explored the effect of structural modifications of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6- dicarboxylate (LY354740), a potent
EXCITATORY AMINOACID RECEPTOR MODULATORS
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, (2008/06/13)
Compounds of the formula STR1 in which R 1 and R 2 are as defined in the specification, and non-toxic metabolically labile ester and amides thereof are useful as modulators of metabotropic glutamate receptor function.