- A convenient strategy to 2,4,5-triaryl and 2-alkyl-4,5-diaryl oxazole derivatives through silver-mediated oxidative CO cross coupling/cyclization
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This is a silver(I) mediated Cα(sp3)H activation of primary amines followed by oxidative CO cross coupling/cyclization for the construction of 2,4,5-triaryl and 2-alkyl-4,5-diaryl oxazole derivatives. The protocol has been successfully utilized to synthesize the oxazole derivatives in good to excellent yields. In this oxidative coupling, the silver species after the reaction was successfully re-synthesized and reused with almost a similar activity.
- Sarkar, Rajib,Mukhopadhyay, Chhanda
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supporting information
p. 3872 - 3876
(2015/06/08)
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- Cyclization of α-Oxo-oximes to 2-Substituted Benzoxazoles
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Reactions of oximes 9, 17, and 19 with electrophiles 15a-f and 24 in the presence of anhydrous potassium carbonate or triethylamine give 2-substituted condensed ring oxazoles 10, 16a-c, 18a-d, 20a-c, and 25 in a new general route to these compounds.
- Katritzky, Alan R.,Wang, Zuoquan,Hall, C. Dennis,Akhmedov, Novruz G.,Shestopalov, Aleksandr A.,Steel, Peter J.
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p. 9093 - 9099
(2007/10/03)
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