217302-91-5Relevant articles and documents
Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives
Jorgensen, Anker Steen,Jacobsen, Poul,Christiansen, Lise Brown,Bury, Paul S.,Kanstrup, Anders,Thorpe, Susan M.,Narum, Lars,Wassermann, Karsten
, p. 2383 - 2386 (2007/10/03)
A series of pyrrolo[2,1,5-cd]indolizine derivatives has been synthesized and evaluated as ligands for the estrogen receptor. Properly substituted mono- and di-hydroxy derivatives showed binding in the low nanomolar range in accordance with their structural resemblance to estrogen. (C) 2000 Elsevier Science Ltd.
Pyrrolo[2,1,5-cd]indolizine derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
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, (2008/06/13)
The present invention relates to therapeutically active compounds of formula I a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.
Liquid Crystalline Compounds Bearing Pyridine Ring: Azoxy Compounds with Alkyl Substituents
Kamogawa, Hiroyoshi,Kasai, Tsuneharu,Andoh, Toshio,Nakamura, Tomoyuki
, p. 2905 - 2910 (2007/10/02)
Azoxy compounds bearing a 2,5-disubstituted pyridine ring as a principal constituent and at least one alkyl group at a molecular end were synthesized and their mesomorphic (nematic) ranges were examined.As for azoxy compounds containing an alkyl and an alkoxy group at both ends, respectively, mesomorphic ranges appeared with lower alkyl groups than those for azo compounds, their precursors.The ranges were also lower than those with both alkoxy ends.As regards an azoxy compound containing alkyl groups at both ends, no mesomorphic phenomenon appeared within the scope of this study.