218151-56-5 Usage
Uses
Used in Pharmaceutical Research:
1H-Indene-1,2-diamine,2,3-dihydro-,(1S,2R)-(9CI) is utilized as a key intermediate in the synthesis of various pharmaceuticals, leveraging its reactivity and structural features to create new drug candidates. Its ability to form different derivatives through chemical reactions makes it a valuable component in the development of innovative medications.
Used in Organic Synthesis:
As a building block in organic synthesis, 1H-Indene-1,2-diamine,2,3-dihydro-,(1S,2R)-(9CI) is employed to construct complex organic molecules. Its capacity for undergoing reduction, acylation, and alkylation reactions enables the synthesis of a broad range of organic compounds, contributing to the advancement of material science and chemical research.
Used in Asymmetric Synthesis:
The enantiopure form of 1H-Indene-1,2-diamine,2,3-dihydro-,(1S,2R)-(9CI) is applied in asymmetric synthesis to produce enantiomerically pure compounds. This is crucial in pharmaceutical development, as the different enantiomers of a drug can exhibit distinct biological activities and pharmacokinetics.
Used in Organometallic Chemistry:
1H-Indene-1,2-diamine,2,3-dihydro-,(1S,2R)-(9CI) also serves as a ligand in organometallic chemistry, facilitating the creation of metal complexes with unique catalytic properties. These complexes are vital in various chemical transformations, further expanding the utility of this compound in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 218151-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,1,5 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 218151-56:
(8*2)+(7*1)+(6*8)+(5*1)+(4*5)+(3*1)+(2*5)+(1*6)=115
115 % 10 = 5
So 218151-56-5 is a valid CAS Registry Number.
218151-56-5Relevant articles and documents
Asymmetric transfer hydrogenation of ketones using amino alcohol and monotosylated diamine derivatives of indane
Palmer, Matthew J.,Kenny, Jennifer A.,Walsgrove, Tim,Kawamoto, Aparecida M.,Wills, Martin
, p. 416 - 427 (2007/10/03)
A series of 1,2-amino alcohol and 1,2-monotosylated diamine derivatives of indane have been applied as ligands in the asymmetric ruthenium(II)-catalysed transfer hydrogenation reaction of a series of ketones. Of these, the cis-1-aminoindan-2-ol derivative gives some of the highest asymmetric inductions reported for any amino alcohol ligand in this application.
Synthesis of enantiomerically pure cis- and trans-1,2- diaminoindanes
Bit, Christelle,Mitrochkine, Anton A.,Gil, Gerard,Pierrot, Marcel,Reglier, Marius
, p. 3263 - 3273 (2007/10/03)
The four isomers of cis- and trans-1,2-diaminoindanes 5 and 11 were prepared in three steps and high enantiomeric excess by a key lipase- catalyzed selective transesterification of racemic cis-2-azido-1-indanol and trans-1-azido-2-indanol, respectively.
