219489-07-3

Basic information

• Product Name: (Z)-1-Ethoxyethene-2-boronic acid pinacol ester
• Synonyms: (Z)-1-Ethoxyethene-2-boronic acid pinacol ester;(Z)-2-Ethoxyethylene-1-boronic acid, pinacol ester;[(Z)-2-Ethoxyethenyl]boronic acid, pinacol ester, 2-[(Z)-2-Ethoxyvinyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-[(Z)-2-Ethoxyethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;[(Z)-2-Ethoxyvinyl]boronic acid, pinacol ester;(Z)-2-(2-Ethoxyvinyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;2-Ethoxyethenyl-1-boronic acid pinacol ester, 98%
• CAS NO: 219489-07-3
• Molecular Formula: C10H19BO3
• Molecular Weight: 198.07
• Mol File: 219489-07-3.mol

Chemical Properties

• Boiling Point: 198°C at 760 mmHg
• Flash Point: 73.5°C
• Appearance: /
• Density: 0.94g/cm³
• Vapor Pressure: 0.518mmHg at 25°C
• Refractive Index: 1.435
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (Z)-1-Ethoxyethene-2-boronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1-Ethoxyethene-2-boronic acid pinacol ester(219489-07-3)
• EPA Substance Registry System: (Z)-1-Ethoxyethene-2-boronic acid pinacol ester(219489-07-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 219489-07-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(Z)-1-Ethoxyethene-2-boronic acid pinacol ester is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its ability to participate in cross-coupling reactions allows for the creation of complex molecular structures that are essential in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (Z)-1-Ethoxyethene-2-boronic acid pinacol ester serves as a crucial building block for the synthesis of agrochemicals. Its reactivity in cross-coupling reactions enables the production of molecules with tailored properties, such as increased stability and bioactivity, which are vital for the development of effective crop protection agents and other agricultural products.
Used in Organic Synthesis Research:
(Z)-1-Ethoxyethene-2-boronic acid pinacol ester is utilized as a versatile reagent in organic synthesis research. Its stability and ease of handling make it an ideal candidate for exploring new synthetic pathways and developing innovative methodologies in the field of organic chemistry.
Used in Fine Chemicals Production:
This boronic acid derivative is also employed in the production of fine chemicals, where its ability to undergo cross-coupling reactions is leveraged to synthesize specialty chemicals with unique properties. These fine chemicals are often used in various applications, such as fragrances, dyes, and other high-value products.

InChI:InChI=1/C10H19BO3/c1-6-12-8-7-11-13-9(2,3)10(4,5)14-11/h7-8H,6H2,1-5H3/b8-7-

Upstream product

• 109-92-2 ethyl vinyl ether 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Relevant articles and documents

NAPHTHYRIDINONE-ANILINE COMPOUNDS FOR TREATMENT OF DERMAL DISORDERS

Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating diseases or disorders in a subject where the subject is in need of an inhibitor of MEK where the compound is according to formula (I): where R1, R2, R2a, R3, R3a, R3b, and subscript n are as described herein.

NOVEL PROCESSES FOR THE MANUFACTURE OF PROPANE-1-SULFONIC ACID {3-[5-(4-CHLORO-PHENYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBONYL]-2,4-DIFLUORO-PHENYL}-AMIDE

According to the present invention there are provided novel processes for the manufacture of the compound of formula (1) as well as novel synthesis routes for key intermediates used in those processes.