Deoxynucleic alkyl thiourea compounds and uses thereof
The invention provides novel deoxynucleic alkyl thiourea (dNXt) oligonucleotide compounds for use in antisense or antigene therapy.
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(2008/06/13)
Deoxynucleic alkyl and alkoxy thiourea compounds
The invention provides novel deoxynucleic alkyl thiourea (dNXt) oligonucleotide compounds for use in antisense or antigene therapy.
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(2008/06/13)
Positively charged deoxynucleic methylthioureas: Synthesis and binding properties of pentameric thymidyl methylthiourea
The negatively charged phosphodiester linkages in DNA {-O(PO2-)O-} have been replaced by a novel methylthiourea {-NHC(=SMe+)NH-} backbone. The backbone is positively charged, achiral, and stable and can be easily synthesiz
Arya, Dev P.,Bruice, Thomas C.
p. 12419 - 12427
(2007/10/03)
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