220193-87-3Relevant articles and documents
Potent inhibition of Grb2 SH2 domain binding by non-phosphate- containing ligands
Yao, Zhu-Jun,King, Richter C.,Cao, Tin,Kelley, James,Milne, George W. A.,Voigt, Johannes H.,Burke Jr., Terrence R.
, p. 25 - 35 (2007/10/03)
Development of Grb2 Src homology 2 (SH2) domain binding inhibitors has important implications for treatment of a variety of diseases, including several cancers. In cellular studies, inhibitors of Grb2 SH2 domain binding have to date been large, highly cha