cas 22027-52-7, METHYL 4-TRIFLUOROMETHYLBENZOYLACETATE | Articles data ｜lookchem

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22027-52-7

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PYRAZOLONE DERIVATIVES AS NITROXYL DONORS
The disclosed subject matter provides pyrazolone derivative compounds, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
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Page/Page column 179; 195; 282; 283; 286; 299; 302; 305; 316; 319

(2016/01/29)

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.
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Page/Page column 78

(2012/11/08)

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Chemical Properties

Melting Point: 57-62 °C
Boiling Point: 363.8 °C at 760 mmHg
Flash Point:160.4 °C
Density: 1.181 g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 1.76E-05mmHg at 25°C
Refractive Index: 1.5140 (estimate)
PSA: 43.37000
LogP: 2.45120

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