220488-24-4Relevant articles and documents
Discovery of a novel Her-1/Her-2 dual tyrosine kinase inhibitor for the treatment of Her-1 selective inhibitor-resistant non-small cell lung cancer
Mi, Young Cha,Lee, Kwang-Ok,Jong, Woo Kim,Chang, Gon Lee,Ji, Yeon Song,Young, Hoon Kim,Gwan, Sun Lee,Seung, Bum Park,Maeng, Sup Kim
scheme or table, p. 6880 - 6888 (2010/04/24)
A novel series of (S)-1-acryloyl-N-[4-(arylamino)-7-(alkoxy)quinazolin-6- yl]pyrrolidine-2-carboxamides were synthesized and evaluated as Her-1/Her-2 dual inhibitors. In contrast to the Her-1 selective inhibitors, our novel compounds are irreversible inhi
QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF
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Page/Page column 34-35, (2008/06/13)
The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof for inhibiting the growth of cancer cells, a method for the preparation thereof and a pharmaceutical composition comprising same as an active ingredient.