Stereocontrolled Synthesis of N-Vinyl-, N-(1'-Propenyl)-, and N-Unsubstituted-β-lactams from 2-Aza-1,3-butadienes via the Staudinger Reaction
2-Aza-1,3-butadienes 2 and 5 were synthesized in good yields and on a large scale.Reaction of 2 and 5 with acid chlorides in the presence of triethylamine (Staudinger reaction) resulted in the high-yielding formation of N-vinyl- and N-(1'-propenyl)-β-lact
2-AZA-1,3-DIENES AS NOVEL PRECURSORS FOR THE SYNTHESIS OF N-UNSUBSTITUTED β-LACTAMS. A THREE STEP SYNTHESIS OF 4-ACETOXY-3-PHENOXY-2-AZETIDINONE
2-Aza-1,3-dienes, prepared in excellent yields from aldehydes and readily available allylamine, were utilized to synthesize N-(1-propenyl)-β-lactams.Oxidative cleavage of the N-protecting group produced N-unsubstituted β-lactams. 4-Acetoxy-3-phenoxy-2-aze
Georg, Gunda I.,Kant, Joydeep,He, Ping,Ly, Ana Maria,Lampe, Lynn
p. 2409 - 2412
(2007/10/02)
More Articles about upstream products of 220934-05-4