220950-35-6

Basic information

• Product Name: 4-(3-Hydroxyphenyl)benzoic acid
• Synonyms: 4-(3-Hydroxyphenyl)benzoic acid
• CAS NO: 220950-35-6
• Molecular Formula: C₁₃H₁₀O₃
• Molecular Weight: 214.22
• Mol File: 220950-35-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 4-(3-Hydroxyphenyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Hydroxyphenyl)benzoic acid(220950-35-6)
• EPA Substance Registry System: 4-(3-Hydroxyphenyl)benzoic acid(220950-35-6)

Safety Data

• Hazardous Substances Data: 220950-35-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-(3-Hydroxyphenyl)benzoic acid is used as a building block for the synthesis of pharmaceuticals, leveraging its capacity to interact with biological targets to create new drugs with potential therapeutic applications.
Used in Dye Industry:
In the dye industry, 4-(3-Hydroxyphenyl)benzoic acid is utilized as a key intermediate for the production of various dyes, contributing to the development of a wide range of colorants for different applications.
Used in Polymer Industry:
4-(3-Hydroxyphenyl)benzoic acid is employed as a versatile intermediate in the synthesis of polymers, playing a crucial role in the creation of new materials with specific properties for various industrial uses.
Used in Chemical Industry:
As a component in the chemical industry, 4-(3-Hydroxyphenyl)benzoic acid is used for the development of new materials and compounds, taking advantage of its unique structure and properties to innovate and enhance existing chemical processes and products.

Upstream product

• 92-92-2 biphenyl-4-carboxylic acid 
• 619-58-9 4-iodobenzoic acid 
• 87199-16-4 3-Formylphenylboronic acid 
• 222180-23-6 3’-formyl-[1,1’-biphenyl]-4-carboxylic acid 
• 81443-43-8 methyl 3'-Methoxy(1,1'-biphenyl)-4-carboxylate 
• 591-20-8 3-Bromophenol 
• 14047-29-1 4-carboxyphenylboronic acid 

Downstream Products

• 579511-01-6 methyl 3'-hydroxy-[1,1'-biphenyl]-4-carboxylate 
• 1354553-12-0 3'-hydroxy-biphenyl-4-carboxylic acid 3-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ylcarbamoyl)-benzylamide 

Relevant articles and documents

Selectivity in the photo-Fenton and photocatalytic hydroxylation of biphenyl-4-carboxylic acid and derivatives (viz. 4-phenylsalicylic acid and 5-phenylsalicylic acid)

The selectivity of hydroxylation of the distal rings of 4-phenylbenzoic acid, 4-phenylsalicylic acid, and 5-phenylsalicylic acid were determined using partial TiO2-mediated photocatalytic degradation and photo-Fenton conditions. This separation of the binding site from the phenyl group being hydroxylated allows a less-biased evaluation. The hydroxylation regiochemistry behaves as qualitatively expected for an electrophilic reaction, given the assumption that 4-carboxyphenyl is a slightly electron-withdrawing substituent. Selectivity for hydroxylation of the distal phenyl in 4- and 5-phenylsalicylic acid is reversed, due to the reversal of the electronic demand, while adsorption to the TiO2 surface is assumed to be analogous for the two structures. Copyright

Non-nucleoside reverse transcriptase inhibitors

Compounds represented by formula I: wherein R2 is selected from the group consisting of H, (C1-4)alkyl, halo, haloalkyl, OH, (C1-6)alkoxy, NH(C1-4alkyl) or N(C1-4alkyl)2; R4 is H

Amidocarboxylic acid derivatives

Amidocarboxylic acid derivatives of the formula: wherein R1 represents a hydrogen atom, etc.; R2 represents an alkylene group; R3 represents a hydrogen atom, etc.; R4 represents a hydrogen atom, etc.; X represents a substituted or unsubstituted aryl group, etc.,; Y represents an oxygen atom, etc.; Z represents an alkylene group, etc.; and W represents an alkyl group, etc.; and pharmacologically acceptable salts thereof and pharmacologically acceptable esters thereof are useful as the active ingredient of pharmaceutical compositions. They may be used to treat specified diseases, including diabetes mellitus, hyperlipemia, arteriosclerosis, hypertension, etc.

Biphenyl derivatives substituted by an aromatic or heteroaromatic radical and pharamaceutical and cosmetic compositions containing same

“Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical and cosmetic compositions containing them” in which: Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group, R2and R3represent, in particular, H or alkyl, or R2and R3, taken together, form a 5- or 6-membered ring, R4and R5represent, in particular, H or halogen, R6represents, in particular, H or lower alkyl, and the salts of the compounds of formula (I). These compounds can be used in particular in the treatment of dermatological complaints associated with a keratinization disorder, and for combating ageing of the skin.