220998-10-7Relevant articles and documents
BN 80927: A novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II
Lavergne, Olivier,Harnett, Jeremiah,Rolland, Alain,Lanco, Christophe,Lesueur-Ginot, Laurence,Demarquay, Daniele,Huchet, Marion,Coulomb, Helene,Bigg, Dennis C. H.
, p. 2599 - 2602 (1999)
BN 80927, a novel homocamptothecin derivative, inhibits both topoisomerase I and topoisomerase II mediated DNA relaxation and shows pronounced cytotoxicity against HT29, SKOV-3, DU145 and MCF7 human tumor cell lines.
Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
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, (2008/06/13)
A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
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, (2008/06/13)
A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
Comptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues
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Example 82, (2008/06/13)
The compound of the formula wherein the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable salts which are useful for the treatment of viral infections, parasitic diseases and the treatment of cancer.