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1-bromo-2,4-difluoro-3-methoxybenzene is an organic compound characterized by the chemical formula C7H5BrF2O. It features a benzene ring with a bromine atom, two fluorine atoms, and a methoxy group attached as substituents. 1-bromo-2,4-difluoro-3-methoxybenzene is recognized for its role in organic synthesis and as a key intermediate in the production of various pharmaceuticals, agrochemicals, and fine chemicals. As a colorless liquid with a strong odor, it is flammable and can cause irritation to the eyes, skin, and respiratory system, necessitating careful handling and storage in well-ventilated areas away from ignition sources and incompatible materials.

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  • 221221-00-7 Structure
  • Basic information

    1. Product Name: 1-bromo-2,4-difluoro-3-methoxybenzene
    2. Synonyms: 1-bromo-2,4-difluoro-3-methoxybenzene;3-Bromo-2,6-difluoroanisole
    3. CAS NO:221221-00-7
    4. Molecular Formula: C7H5BrF2O
    5. Molecular Weight: 223.0148064
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 221221-00-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-bromo-2,4-difluoro-3-methoxybenzene(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-bromo-2,4-difluoro-3-methoxybenzene(221221-00-7)
    11. EPA Substance Registry System: 1-bromo-2,4-difluoro-3-methoxybenzene(221221-00-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 221221-00-7(Hazardous Substances Data)

221221-00-7 Usage

Uses

Used in Organic Synthesis:
1-bromo-2,4-difluoro-3-methoxybenzene is utilized as a building block in organic synthesis for the creation of a variety of complex organic molecules. Its unique combination of functional groups allows for versatile chemical reactions, making it a valuable component in the synthesis of specialty chemicals.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-bromo-2,4-difluoro-3-methoxybenzene is employed as an intermediate in the synthesis of specific drug molecules. Its presence in the molecular structure can contribute to the desired pharmacological properties of the final drug product, such as potency, selectivity, and bioavailability.
Used in Agrochemical Development:
1-bromo-2,4-difluoro-3-methoxybenzene also finds application in the agrochemical sector, where it serves as an intermediate in the development of pesticides and other crop protection agents. Its chemical structure can be tailored to target specific pests or diseases, enhancing the effectiveness of these products.
Used in Fine Chemicals Manufacturing:
1-bromo-2,4-difluoro-3-methoxybenzene is used as an intermediate in the production of fine chemicals, which are high-purity chemicals used in various industries such as fragrances, flavors, dyes, and more. The specific functional groups present in 1-bromo-2,4-difluoro-3-methoxybenzene make it suitable for creating high-quality specialty chemicals with precise properties.

Check Digit Verification of cas no

The CAS Registry Mumber 221221-00-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,2,2 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 221221-00:
(8*2)+(7*2)+(6*1)+(5*2)+(4*2)+(3*1)+(2*0)+(1*0)=57
57 % 10 = 7
So 221221-00-7 is a valid CAS Registry Number.

221221-00-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Bromo-2,4-difluoro-3-methoxybenzene

1.2 Other means of identification

Product number -
Other names 3-Methoxy-2,4-difluoro-bromobenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:221221-00-7 SDS

221221-00-7Relevant articles and documents

CYCLOALKANE-1,3-DIAMINE DERIVATIVE

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Paragraph 1320-1323; 1335-1337, (2021/09/03)

The present invention provides a compound or a pharmaceutically acceptable salt thereof having an inhibitory action on the interaction between menin and an MLL protein. The compound represented by the formula (1) or a pharmaceutically acceptable salt thereof. wherein, in the formula (1), the dotted circle, R1, R2, R3, R4, R5, R6, R7, R8, Ring Q1, W, m and n are each as defined in the description.

Process for making certain benzoic acid compounds

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Page column 12, (2010/01/30)

The subject invention involves processes for making 2,4-difluoro-3-Q1-benzoic acid, wherein Q1 is derived from an electrophilic reagent, comprising the steps of: (a) treating 1-bromo-2,4-difluorobenzene with a strong, non-nucleophilic base; then treating

Antimicrobial quinolones, their compositions and uses

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, (2008/06/13)

This invention relates to novel antimicrobial compounds of formula; wherein X, R1, R3, R5, R6, and R8 are defined in the claims, and to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically-acceptable salts, hydrates, and biohydrolyzable esters, amides and imides thereof, and to compositions and uses of such compounds. The invention also relates to compounds derived from these compounds having antimicrobial uses.

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