221295-08-5Relevant articles and documents
Synthesis and luminescence properties of near-infrared N-heterocyclic luciferin analogues for in vivo optical imaging
Saito, Ryohei,Kuchimaru, Takahiro,Higashi, Shoko,Lu, Shijia W.,Kiyama, Masahiro,Iwano, Satoshi,Obata, Rika,Hirano, Takashi,Kizaka-Kondoh, Shinae,Maki, Shojiro A.
, p. 608 - 618 (2019/04/05)
As a means of achieving highly sensitive bioluminescence imaging of deep tissues utilizing the firefly luciferin-luciferase (L-L) reaction, we previously reported a luciferin analogue, AkaLumine, which exhibits high cell-permeability and emits near-infrar
NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF
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, (2016/07/05)
There is provided a morpholine derivative represented by General Formula [1A] or a salt thereof. (In the formula, a ring A represents a ring represented by General Formula [I]; * represents a bonding position; Z2 represents CH or the like; Z1 represents CR6 or the like; R6 represents a hydrogen atom or the like; X1 represents CHR7 or the like; R7 represents a hydrogen atom or the like; X2 represents CH2 or the like; R1 and R2 are the same as or different from each other, and each of R1 and R2 represents a hydrogen atom or the like; R3, R4, and R5 are the same as or different from each other, and each of R3, R4, and R5 represents a hydrogen atom, NRaRb, or the like; and each of Ra and Rb represents a hydrogen atom, a C1-8 alkyl group which may have a substituent, or the like.)
NOVEL HETEROCYCLIC COMPOUNDS AND SALTS THEREOF, AND LUMINESCENT SUBSTRATE COMPOSITIONS
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Paragraph 0082; 0083, (2016/10/07)
PROBLEM TO BE SOLVED: To provide novel compounds excellent in solubility in a buffer solution having a near-neutral pH and available as luminescent substrates in firefly bioluminescence systems. SOLUTION: The present invention provides heterocyclic compou
HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES
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Page/Page column 135, (2015/11/09)
The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.