221323-59-7Relevant articles and documents
PYRROLIDINE ARYL-ETHER AS NK3 RECEPTOR ANTAGONISTS
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Page/Page column 33, (2009/03/07)
The invention relates to a compound of formula I wherein Ar1,Ar2,R1,R2, R3, R4, n, o, p, and q are as defined herein and to a pharmaceutically active salt thereof, including all stereoisome
PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING
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Page/Page column 96, (2009/11/29)
The invention provides novel inhibitors of hedgehog signaling that are useful as s therapeutic agent for treating malignancies where the compounds have the general formula (I): where A, X, Y R1, R2, R3, R4, m and n are as described herein.
Pyridyl inhibitors of hedgehog signalling
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Page/Page column 76; 121, (2010/10/20)
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.