- Trifluoromethyl ketone analogs as selective cPLA2 inhibitors
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Selective inhibitors of the cPLA2enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where (R′), p, D, Y, Z, Ra, Rband A are as defined in the specification.
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- Trifluoromethyl ketone analogs as selective cPLA2 inhibitors
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Selective inhibitors of the cPLA2enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula
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