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2220-12-4

9,10-dimethoxy-13-methyl-5,13a-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline is a complex organic compound with a molecular formula of C21H19NO4. It is characterized by a unique structure that includes a dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline core, which is a type of fused ring system. The compound features a methyl group at the 13th position, and two methoxy groups at the 9th and 10th positions, which contribute to its chemical properties. This specific arrangement of atoms and functional groups gives the compound its distinct chemical and physical characteristics, making it a potentially interesting molecule for further study in the fields of organic chemistry and pharmacology.

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  • 2220-12-4 Structure

  • Basic information

    1. Product Name: 9,10-dimethoxy-13-methyl-5,13a-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline
    2. Synonyms:
    3. CAS NO:2220-12-4
    4. Molecular Formula: C21H20NO4*I
    5. Molecular Weight: 351.3957
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2220-12-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 613°C at 760 mmHg
    3. Flash Point: 186.6°C
    4. Appearance: N/A
    5. Density: 1.33g/cm3
    6. Vapor Pressure: 5.79E-15mmHg at 25°C
    7. Refractive Index: 1.662
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 9,10-dimethoxy-13-methyl-5,13a-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline(CAS DataBase Reference)
    11. NIST Chemistry Reference: 9,10-dimethoxy-13-methyl-5,13a-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline(2220-12-4)
    12. EPA Substance Registry System: 9,10-dimethoxy-13-methyl-5,13a-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline(2220-12-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2220-12-4(Hazardous Substances Data)

2220-12-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2220-12-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,2 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2220-12:
(6*2)+(5*2)+(4*2)+(3*0)+(2*1)+(1*2)=34
34 % 10 = 4
So 2220-12-4 is a valid CAS Registry Number.

2220-12-4Downstream Products

2220-12-4Relevant articles and documents

NOVEL ISOQUINOLINE DERIVATIVES

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Page/Page column 21-22, (2010/11/18)

A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R7 have the significance given in claim 1, can be used in the form of a pharmaceutical composition.

NOVEL ISOQUINOLINE DERIVATIVES

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Page/Page column 11-12, (2010/12/29)

The invention provides novel compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein, compositions including the compounds and methods of preparing and using the compounds.

13,13a-DIHYDROBERBERINE DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITION AND USE

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Page/Page column 13, (2009/07/10)

The present invention provides 13,13a-dihydroberberine derivatives or their physiologically acceptable salts represented by the following formula, pharmaceutical compositions comprising the same, and uses thereof. The 13,13a-dihydroberberine derivatives have an activity of promoting glucose absorption in muscle cells, and the whole animal tests show that the present compounds have effects on improving glucose-tolerance and insulin-resistance, facilitating weight loss, relieving fatty liver and the like. Thus, the present compounds can be used in treating diabetes mellitus, adiposity, fatty liver and complications thereof induced by insulin resistance.

The Polonovski-Potier reaction of berbine N-oxides. Synthesis of 8-hydroxymethyl and 8-methylberbines

Suau, Rafael,Nájera, Francisco,Rico, Rodrigo

, p. 9713 - 9723 (2007/10/03)

The Polonovski-Potier reaction of trans and cis berbines N-oxides was studied. The 8-cyano derivative obtained from trans N-oxides were used to synthesize 8-hydroxymethyl and 8-methyl berbines. This procedure was applied to the stereocontroled synthesis of (8R, 14S)-(-)-8-methylcanadine from (14S)-(-)-canadine. (C) 2000 Elsevier Science Ltd.

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