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3'-Formyl[1,1'-biphenyl]-4-carboxylic acid is a chemical compound characterized by its molecular formula C14H10O3. It is a derivative of biphenyl, an extensively utilized industrial chemical. 3'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID features a formyl group and a carboxylic acid group, which contribute to its versatility as a building block in organic synthesis. Its distinctive chemical structure endows it with potential applications across the pharmaceutical and materials industries, and it serves as a valuable intermediate in the synthesis of a variety of organic compounds. 3'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID's properties and reactivity make it an important component in the realm of organic chemistry.

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  • 222180-23-6 Structure
  • Basic information

    1. Product Name: 3'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID
    2. Synonyms: ART-CHEM-BB B025027;3'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID;3'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID;AKOS B025027;AKOS BAR-0091;SALOR-INT L480649-1EA;4-(3-Formylphenyl)benzoic acid;4-(3-Formylphenyl)benzoic acid, 3-(4-Carboxyphenyl)benzaldehyde
    3. CAS NO:222180-23-6
    4. Molecular Formula: C14H10O3
    5. Molecular Weight: 226.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 222180-23-6.mol
  • Chemical Properties

    1. Melting Point: 231 °C
    2. Boiling Point: 441.9 °C at 760 mmHg
    3. Flash Point: 235.2 °C
    4. Appearance: /
    5. Density: 1.264 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 3'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID(222180-23-6)
    11. EPA Substance Registry System: 3'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID(222180-23-6)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 222180-23-6(Hazardous Substances Data)

222180-23-6 Usage

Uses

Used in Pharmaceutical Industry:
3'-Formyl[1,1'-biphenyl]-4-carboxylic acid is used as a key intermediate for the synthesis of pharmaceutical compounds due to its ability to be readily modified and incorporated into complex molecular structures. Its presence in drug molecules can contribute to desired pharmacological properties, such as increased bioavailability or specific binding affinities.
Used in Materials Industry:
In the materials industry, 3'-Formyl[1,1'-biphenyl]-4-carboxylic acid is utilized as a component in the development of novel materials with tailored properties. Its chemical structure allows for the creation of materials with improved thermal stability, mechanical strength, or specific optical characteristics, depending on the application requirements.
Used in Organic Synthesis:
3'-Formyl[1,1'-biphenyl]-4-carboxylic acid is used as a versatile building block in organic synthesis for the creation of a wide range of organic compounds. Its reactivity with various reagents and its compatibility with different synthetic routes make it a valuable precursor in the synthesis of specialty chemicals, agrochemicals, and other fine chemicals.
Used in Research and Development:
3'-Formyl[1,1'-biphenyl]-4-carboxylic acid is employed as a research compound in academic and industrial laboratories. It is used to explore new synthetic methodologies, investigate the properties of novel chemical entities, and develop new applications in various fields, including medicinal chemistry, materials science, and chemical engineering.

Check Digit Verification of cas no

The CAS Registry Mumber 222180-23-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,2,1,8 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 222180-23:
(8*2)+(7*2)+(6*2)+(5*1)+(4*8)+(3*0)+(2*2)+(1*3)=86
86 % 10 = 6
So 222180-23-6 is a valid CAS Registry Number.

222180-23-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(3-formylphenyl)benzoic acid

1.2 Other means of identification

Product number -
Other names 3'-formylbiphenyl-4-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:222180-23-6 SDS

222180-23-6Relevant articles and documents

HETEROCYCLIC INTEGRIN AGONISTS

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Paragraph 0234; 0236; 0265; 0266; 0275; 0277, (2018/07/29)

The present invention provides polycyclic oxothioxoimidazolidines, dioxoimidazolines, oxothioxooxazolidines, dioxooxazolidines, and related compounds, which are useful as integrin agonists. Methods for the treatment of integrin-mediated diseases such as cancer are also described.

Selectivity in the photo-Fenton and photocatalytic hydroxylation of biphenyl-4-carboxylic acid and derivatives (viz. 4-phenylsalicylic acid and 5-phenylsalicylic acid)

Hathway, Timothy,Chernyshov, Deborah Lipman,Jenks, William S.

supporting information, p. 1151 - 1156 (2013/01/09)

The selectivity of hydroxylation of the distal rings of 4-phenylbenzoic acid, 4-phenylsalicylic acid, and 5-phenylsalicylic acid were determined using partial TiO2-mediated photocatalytic degradation and photo-Fenton conditions. This separation of the binding site from the phenyl group being hydroxylated allows a less-biased evaluation. The hydroxylation regiochemistry behaves as qualitatively expected for an electrophilic reaction, given the assumption that 4-carboxyphenyl is a slightly electron-withdrawing substituent. Selectivity for hydroxylation of the distal phenyl in 4- and 5-phenylsalicylic acid is reversed, due to the reversal of the electronic demand, while adsorption to the TiO2 surface is assumed to be analogous for the two structures. Copyright

1H-INDOLE-2-CARBOXYLIC ACID DERIVATIVES USEFUL AS PPAR MODULATORS

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Page/Page column 65-66, (2008/06/13)

The present invention relates to certain indole derivatives that are modulators of PPAR, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine.

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