222714-33-2

Basic information

• Product Name: (S)-4-(1-AMINOETHYL)BENZOIC ACID
• Synonyms: 4-[(1S)-1-AMINOETHYL]-BENZOIC ACID;(S)-4-(1-AMINOETHYL)BENZOIC ACID;Benzoic acid, 4-[(1S)-1-aminoethyl]-;4-[(1S)-1-aMinoethyl]-;(S)-4-(1-aminoethyl)benzoic acid HCl
• CAS NO: 222714-33-2
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Product Categories: API intermediates
• Mol File: 222714-33-2.mol

Chemical Properties

• Boiling Point: 317°C at 760 mmHg
• Flash Point: 145.5°C
• Appearance: /
• Density: 1.186g/cm³
• Vapor Pressure: 0.000166mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.02±0.10(Predicted)
• CAS DataBase Reference: (S)-4-(1-AMINOETHYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(1-AMINOETHYL)BENZOIC ACID(222714-33-2)
• EPA Substance Registry System: (S)-4-(1-AMINOETHYL)BENZOIC ACID(222714-33-2)

Safety Data

• Hazardous Substances Data: 222714-33-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
(S)-4-(1-AMINOETHYL)BENZOIC ACID is used as a neurotransmitter precursor and modulator in the field of neuropharmacology for its potential therapeutic applications. It plays a crucial role in the regulation of neurotransmission, which can be beneficial in the treatment of various neurological disorders.
Used in the Synthesis of Bioactive Compounds:
(S)-4-(1-AMINOETHYL)BENZOIC ACID is used as a building block in the synthesis of various bioactive compounds. Its unique structure allows for the development of new pharmaceutical agents with potential applications in different therapeutic areas.
Used in Neuropharmacology:
In the field of neuropharmacology, (S)-4-(1-AMINOETHYL)BENZOIC ACID is used as a research compound to study the mechanisms of neurotransmission and develop new drugs targeting specific neurological pathways. Its ability to act as a neurotransmitter precursor and modulator makes it a valuable tool in understanding and treating neurological disorders.

InChI:InChI=1/C9H11NO2/c1-6(10)7-2-4-8(5-3-7)9(11)12/h2-6H,10H2,1H3,(H,11,12)/t6-/m0/s1

Downstream Products

• 847729-00-4 (S)-4-[1-(benzyloxycarbonylamino)ethyl]benzoic acid 
• 222714-37-6 4-[(1S)-1-aminoethyl]-benzoic acid, methyl ester 
• 1362627-51-7 C₂₃H₃₀N₂O₅ 
• 847729-02-6 tert-butyl 4-[(1S)-1-aminoethyl]benzoate 
• 847729-01-5 (S)-tert-butyl 4-[1-(benzyloxycarbonylamino)ethyl]benzoate 
• 847729-04-8 tert-butyl 4-[(1S)-1-[(2,5-dichloropyridin-3-yl)formamido]ethyl]benzoate 

Relevant articles and documents

Piperazine compounds and medicinal use thereof

The present invention relates to a piperazine compound of the formula wherein R1and R2are each hydrogen, halogen, lower alkyl, lower alkoxy, amino, substituted amino, nitro, hydroxy or cyano, R3, R4and R5are each hydrogen, halogen, lower alkyl, lower alkoxy, nitro, amino, substituted amino or hydroxy, R6and R7are each hydrogen, lower alkyl, lower alkyl substituted by halogen, aralkyl, acyl or lower acyl substituted by halogen, R8and R9are each hydrogen or lower alkyl, Y is lower alkylene and the like, and ring A is phenyl, pyrimidyl, thiazolyl, pyridyl, pyrazyl or imidazolyl, a pharmaceutically acceptable salt thereof and pharmaceutical agents containing these compounds. The compound of the present invention has superior TNF-α production inhibitory effect and/or IL-10 production promoting effect, and, since it is free of or shows only strikingly reduced expression of an effect on the central nervous system, the compound is useful as a highly safe and superior TNF-α production inhibitor an/or IL-10 production promoter and is useful as an agent for the prophylaxis or treatment of various diseases caused by abnormal TNF-α production, diseases curable with IL-10, such as chronic inflammatory diseases, acute inflammatory diseases, inflammatory diseases due to infection, autoimmune diseases, allergic diseases, and TNF-α mediated diseases.