Synthesis and biological activity of the 2-amino-4-(4-iodophenyl)amino-6- methylpyrimidine isosteric analogs
Transformation of the structure of 6-methylisocytosine results in the isosteric analogs of 2-amino-4-(4-iodophenyl)amino-6-methylpyrimidine exhibiting tuberculocidal properties. The level of biological activity of the synthesized compounds depends on the
Erkin,Krutikov
p. 538 - 541
(2013/08/23)
5-Substituted 2-amino-6-phenyl-4(3H)-pyrimidinones. Antiviral- and interferon-inducing agents
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Wierenga,Skulnick,Stringfellow,Weed,Renis,Eidson
p. 237 - 239
(2007/10/02)
Interferon induction
A method and therapeutic compositions for inducing interferon formation in vivo. To a host is administered an interferon inducer of the formula: SPC1 Wherein X is a member selected from the group consisting of bromo and iodo and Y is a member selected from the group consisting of methyl and ethyl when X is bromo; or Y is a member selected from the group consisting of methyl, ethyl, n-propyl, benzyl and chloro when X is iodo.
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(2008/06/13)
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