222987-19-1

Basic information

• Product Name: (R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE
• Synonyms: (R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE
• CAS NO: 222987-19-1
• Molecular Formula: C₁₆H₂₁NO₅
• Molecular Weight: 307.34
• Mol File: 222987-19-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE(222987-19-1)
• EPA Substance Registry System: (R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE(222987-19-1)

Safety Data

• Hazardous Substances Data: 222987-19-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE is used as a building block in organic synthesis for the construction of various molecules and pharmaceutical intermediates. Its unique chemical properties and reactivity allow for the creation of a wide range of compounds with diverse applications.
Used in Pharmaceutical Industry:
(R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE is used as a key intermediate in the production of pharmaceuticals. Its unique structure and reactivity contribute to the development of novel drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
(R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE is also employed in the agrochemical industry, where it serves as an essential intermediate for the synthesis of various agrochemical products. Its chemical properties make it suitable for the development of new compounds with improved efficacy and selectivity in agricultural applications.
Used in Drug Development:
(R)-1-BOC-3-(3-CARBOXY-PHENOXY)-PYRROLIDINE has potential applications in the development of novel drug candidates and bioactive compounds. Its unique structure and reactivity can be leveraged to design and synthesize new molecules with potential therapeutic effects in various medical fields.

Downstream Products

• 222987-20-4 1-[3-[[(3R)-1-tert-butoxycarbonylpyrrolidin-3-yl]oxy]benzoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine 

Relevant articles and documents

NOVEL ETHYLENEDIAMINE DERIVATIVES

A compound represented by the following formula (1):Q-Q-T-N(R)-Q-N(R)-T-Q [wherein, R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6- membered cyclic hydrocarbon group which may have a substituent, or the like; Q2 is a single bond or the like; Q3 represents the following group: -C(R3a)(R4a)-{C(R3b)(R4b)}m1-{C(R3c)(R4c)}m2-{C(R3d)(R4d)}m3-{C(R3e)(R4e)}m4-C(R3f)(R4f)- (in which, R3a to R4e represent hydrogen or the like); T0 represents a carbonyl group or the like; and T1 represents -COCONR- or the like]; or salt thereof, solvate thereof, or N-oxide thereof. The compound is useful as a preventive and/or therapeutic agent for cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.

Sulfonyl derivatives

Sulfonyl derivatives represented by general formula (I), salts of the same, and solvates of both: and application of them as drugs: [wherein R1is hydrogen, hydroxyl, nitro or the like; R2and R3are each independently hydrogen, halogeno or the like; R4and R5are each dependently hydrogen, halogeno or the like; Q1is an optionally substituted saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group or the like; Q2is a single bond, oxygen or the like; Q3is, e.g., a group represented by formula (a): T1is carbonyl or the like; and X1and X2are each independently methylidyne or nitrogen]. These compounds exhibit potent Fxa inhibiting activities and serve as excellent anticoagulants which speedily exert satisfactory and persistent anti-thrombotic effects through oral administration and little cause adverse effects.

NOVEL SULFONYL DERIVATIVES

Sulfonyl derivatives represented by the following general formula (I): Q1-Q2-T1-Q3-SO2-QA and drugs containing the same (wherein Q1 is an optionally substituted, saturated or unsaturated, five- or six-membered cyclic hydrocarbon group, a five- or six-membered heterocyclic group, or the like; Q2 is a single band, oxygen, sulfur, C1-C6 alkylene or the like; QA is optionally substituted arylalkenyl, heteroarylalkenyl or the like; and T1 is carbonyl or the like). These compounds have potent FXa-inhibitory effects and promptly exert satisfactory and persistent antithrombotic effects through oral administration, thus being useful as anticoagulant agents little accompanied with side effects.