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2248003-60-1

N -(4-{[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]-amino}phenyl)-2-[4-(propan-2-yl)-1 H -1,2,3-triazol-1-yl]acetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • N-(4-{[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-(4-isopropyl-1,2,3-triazol-1-yl)acetamide

    Cas No: 2248003-60-1

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  • N -(4-{[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]-amino}phenyl)-2-[4-(propan-2-yl)-1 H -1,2,3-triazol-1-yl]acetamide

    Cas No: 2248003-60-1

  • USD $ 10.0-10.0 / Milligram

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  • 2248003-60-1 Structure

  • Basic information

    1. Product Name: N -(4-{[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]-amino}phenyl)-2-[4-(propan-2-yl)-1 H -1,2,3-triazol-1-yl]acetamide
    2. Synonyms:
    3. CAS NO:2248003-60-1
    4. Molecular Formula:
    5. Molecular Weight: 479.514
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2248003-60-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N -(4-{[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]-amino}phenyl)-2-[4-(propan-2-yl)-1 H -1,2,3-triazol-1-yl]acetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N -(4-{[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]-amino}phenyl)-2-[4-(propan-2-yl)-1 H -1,2,3-triazol-1-yl]acetamide(2248003-60-1)
    11. EPA Substance Registry System: N -(4-{[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]-amino}phenyl)-2-[4-(propan-2-yl)-1 H -1,2,3-triazol-1-yl]acetamide(2248003-60-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2248003-60-1(Hazardous Substances Data)

2248003-60-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2248003-60-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,2,4,8,0,0 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2248003-60:
(9*2)+(8*2)+(7*4)+(6*8)+(5*0)+(4*0)+(3*3)+(2*6)+(1*0)=131
131 % 10 = 1
So 2248003-60-1 is a valid CAS Registry Number.

2248003-60-1Downstream Products

2248003-60-1Relevant articles and documents

C5-ANILINOQUINAZOLINE COMPOUNDS AND THEIR USE IN TREATING CANCER

-

, (2018/11/21)

The invention concerns compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 have any of the meanings hereinbefore defined in the description; process for their prepar

Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

Kettle, Jason G.,Anjum, Rana,Barry, Evan,Bhavsar, Deepa,Brown, Crystal,Boyd, Scott,Campbell, Andrew,Goldberg, Kristin,Grondine, Michael,Guichard, Sylvie,Hardy, Christopher J.,Hunt, Tom,Jones, Rhys D. O.,Li, Xiuwei,Moleva, Olga,Ogg, Derek,Overman, Ross C.,Packer, Martin J.,Pearson, Stuart,Schimpl, Marianne,Shao, Wenlin,Smith, Aaron,Smith, James M.,Stead, Darren,Stokes, Steve,Tucker, Michael,Ye, Yang

, p. 8797 - 8810 (2018/10/05)

While the treatment of gastrointestinal stromal tumors (GISTs) has been revolutionized by the application of targeted tyrosine kinase inhibitors capable of inhibiting KIT-driven proliferation, diverse mutations to this kinase drive resistance to establish

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