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224818-73-9

3-(Pyridin-3-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 224818-73-9 Structure

  • Basic information

    1. Product Name: 3-(Pyridin-3-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester
    2. Synonyms: 3-(Pyridin-3-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester;tert-Butyl 3-(pyridin-3-yloxy)pyrrolidine-1-carboxylate
    3. CAS NO:224818-73-9
    4. Molecular Formula: C14H20N2O3
    5. Molecular Weight: 264.3202
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 224818-73-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(Pyridin-3-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(Pyridin-3-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester(224818-73-9)
    11. EPA Substance Registry System: 3-(Pyridin-3-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester(224818-73-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 224818-73-9(Hazardous Substances Data)

224818-73-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 224818-73-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,4,8,1 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 224818-73:
(8*2)+(7*2)+(6*4)+(5*8)+(4*1)+(3*8)+(2*7)+(1*3)=139
139 % 10 = 9
So 224818-73-9 is a valid CAS Registry Number.

224818-73-9Relevant articles and documents

NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS

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, (2011/06/19)

The invention relates to novel heterocyclic acrylamide compounds (I), to the preparation of the compounds and intermediates used therein, to the use of the compounds as antibacterial medicaments and pharmaceutical compositions containing the compounds.

PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION

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Page 6-7; 10, (2010/02/07)

The present invention provides compounds of the formula:wherein m is 0, 1 or 2; p is 0 or 1; Y is O, S, S(O) or S(O)2 and R1 to R7 are various substituents as selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Al

Pyridyl ethers and thioethers as ligands for nicotinic acetylcholine receptor and its therapeutic application

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, (2008/06/13)

The present invention provides compounds of the formula: wherein m is 0, 1 or 2; p is 0 or 1; Y is O, S, S(O) or S(O)2 and R1 to R7 are various substituents as selective modulators of the nicotinic acetylcholine receptor u

Novel potent ligands for the central nicotinic acetylcholine receptor: Synthesis, receptor binding, and 3D-QSAR analysis

Nielsen, Simon Feldb?k,Nielsen, Elsebet ?stergaard,Olsen, Gunnar M.,Liljefors, Tommy,Peters, Dan

, p. 2217 - 2226 (2007/10/03)

In the past few years the focus on central acetylcholine receptors has shifted from-compounds with affinity for muscarinic acetylcholine receptors (mAChR) to compounds with affinity for nicotinic acetylcholine receptors (nAChR). The therapeutic potential

Synthesis and structure-activity relationship of novel pyridyl ethers for the nicotinic acetylcholine receptor

Lee, Jung,Davis, Coralie B.,Rivero, Ralph A.,Reitz, Allen B.,Shank, Richard P.

, p. 1063 - 1066 (2007/10/03)

The preparation of novel pyridyl ethers as ligands for the nicotinic acetylcholine receptor (nAChR) is described. Variations of the ring size of the azacycle and substitution on the pyridine had dramatic effects on receptor binding affinity with IC50S at the α4β2 nAChR ranging from 22 to >10,000 nM. The most potent molecule was (R)-2-chloro-3-(4-cyanophenyl)-5-((3-pyrrolidinyl)oxy)pyridine 27f with an IC50 of 22 nM. (C) 2000 Elsevier Science Ltd. All rights reserved.

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